Aims: This retrospective observational study was aimed to identify hematological predictors of histological heterogeneity of carotid atherosclerotic plaques (CAPs). Results: The mean values of all demographic, clinical and haematological parameters did not differ between patients with or without symptomatic CAD. In univariate analysis, intraplaque hemorrhage was associated with male sex (r=0.18; p=0.032), superficial thrombosis with low hemoglobin (r=- 0.18; p=0.033), fibrosis with enhanced RDW (r=0.24; p=0.005), presence of foam cells with high WBC count (r=0.22; p=0.001), neovascularisation with high WBC count (r=0.17; p=0.048), whilst the presence of inflammatory infiltrate was also associated with high WBC count (r=0.17; p=0.043). Conlusions: The results of this retrospective observational study confirm that some traditional and inexpensive hematological parameters such as WBC count, hemoglobin and RDW may help identifying patients with more severe forms of CAD.

Demographic, Clinical and Hematological Predictors of Carotid Atherosclerotic Plaque Histology / Luca Salvagno, Gian; Mezzetto, Luca; Eccher, Albino; Scorsone, Lorenzo; Macrì, Marco; Fabio, Simoncini; Criscenti, Paolo; Lippi, Giuseppe; Franco Veraldi, Gian. - In: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. - ISSN 2475-0379. - 3:(2019), pp. 22-23.

Demographic, Clinical and Hematological Predictors of Carotid Atherosclerotic Plaque Histology

Albino Eccher;
2019

Abstract

Aims: This retrospective observational study was aimed to identify hematological predictors of histological heterogeneity of carotid atherosclerotic plaques (CAPs). Results: The mean values of all demographic, clinical and haematological parameters did not differ between patients with or without symptomatic CAD. In univariate analysis, intraplaque hemorrhage was associated with male sex (r=0.18; p=0.032), superficial thrombosis with low hemoglobin (r=- 0.18; p=0.033), fibrosis with enhanced RDW (r=0.24; p=0.005), presence of foam cells with high WBC count (r=0.22; p=0.001), neovascularisation with high WBC count (r=0.17; p=0.048), whilst the presence of inflammatory infiltrate was also associated with high WBC count (r=0.17; p=0.043). Conlusions: The results of this retrospective observational study confirm that some traditional and inexpensive hematological parameters such as WBC count, hemoglobin and RDW may help identifying patients with more severe forms of CAD.
2019
3
22
23
Luca Salvagno, Gian; Mezzetto, Luca; Eccher, Albino; Scorsone, Lorenzo; Macrì, Marco; Fabio, Simoncini; Criscenti, Paolo; Lippi, Giuseppe; Franco Vera...espandi
Demographic, Clinical and Hematological Predictors of Carotid Atherosclerotic Plaque Histology / Luca Salvagno, Gian; Mezzetto, Luca; Eccher, Albino; Scorsone, Lorenzo; Macrì, Marco; Fabio, Simoncini; Criscenti, Paolo; Lippi, Giuseppe; Franco Veraldi, Gian. - In: RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS. - ISSN 2475-0379. - 3:(2019), pp. 22-23.
File in questo prodotto:
File Dimensione Formato  
Demographic, Clinical and Hematological.pdf

Accesso riservato

Dimensione 490.4 kB
Formato Adobe PDF
490.4 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1317390
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact