: Different monitoring and control policies have been implemented in schools to minimize the spread of SARS-CoV-2. Transmission in schools has been hard to quantify due to the large proportion of asymptomatic carriers in young individuals. We applied a Bayesian approach to reconstruct the transmission chains between 284 SARS-CoV-2 infections ascertained during 87 school outbreak investigations conducted between March and April 2021 in Italy. Under the policy of reactive quarantines, we found that 42.5% (95%CrI: 29.5-54.3%) of infections among school attendees were caused by school contacts. The mean number of secondary cases infected at school by a positive individual during in-person education was estimated to be 0.33 (95%CrI: 0.23-0.43), with marked heterogeneity across individuals. Specifically, we estimated that only 26.0% (95%CrI: 17.6-34.1%) of students and school personnel who tested positive during in-person education caused at least one secondary infection at school. Positive individuals who attended school for at least 6 days before being isolated or quarantined infected on average 0.49 (95%CrI: 0.14-0.83) secondary cases. Our findings provide quantitative insights on the contribution of school transmission to the spread of SARS-CoV-2 in young individuals. Identifying positive cases within 5 days after exposure to their infector could reduce onward transmission at school by at least 30%.

SARS-CoV-2 transmission patterns in educational settings during the Alpha wave in Reggio-Emilia, Italy / Molina Grané, C.; Mancuso, P.; Vicentini, M.; Venturelli, F.; Djuric, O.; Manica, M.; Guzzetta, G.; Marziano, V.; Zardini, A.; D'Andrea, V.; Trentini, F.; Bisaccia, E.; Larosa, E.; Cilloni, S.; Cassinadri, M. T.; Pezzotti, P.; Ajelli, M.; Rossi, P. G.; Merler, S.; Poletti, P.. - In: EPIDEMICS. - ISSN 1755-4365. - 44:(2023), pp. 100712-100712. [10.1016/j.epidem.2023.100712]

SARS-CoV-2 transmission patterns in educational settings during the Alpha wave in Reggio-Emilia, Italy

Venturelli F.;
2023

Abstract

: Different monitoring and control policies have been implemented in schools to minimize the spread of SARS-CoV-2. Transmission in schools has been hard to quantify due to the large proportion of asymptomatic carriers in young individuals. We applied a Bayesian approach to reconstruct the transmission chains between 284 SARS-CoV-2 infections ascertained during 87 school outbreak investigations conducted between March and April 2021 in Italy. Under the policy of reactive quarantines, we found that 42.5% (95%CrI: 29.5-54.3%) of infections among school attendees were caused by school contacts. The mean number of secondary cases infected at school by a positive individual during in-person education was estimated to be 0.33 (95%CrI: 0.23-0.43), with marked heterogeneity across individuals. Specifically, we estimated that only 26.0% (95%CrI: 17.6-34.1%) of students and school personnel who tested positive during in-person education caused at least one secondary infection at school. Positive individuals who attended school for at least 6 days before being isolated or quarantined infected on average 0.49 (95%CrI: 0.14-0.83) secondary cases. Our findings provide quantitative insights on the contribution of school transmission to the spread of SARS-CoV-2 in young individuals. Identifying positive cases within 5 days after exposure to their infector could reduce onward transmission at school by at least 30%.
2023
44
100712
100712
SARS-CoV-2 transmission patterns in educational settings during the Alpha wave in Reggio-Emilia, Italy / Molina Grané, C.; Mancuso, P.; Vicentini, M.; Venturelli, F.; Djuric, O.; Manica, M.; Guzzetta, G.; Marziano, V.; Zardini, A.; D'Andrea, V.; Trentini, F.; Bisaccia, E.; Larosa, E.; Cilloni, S.; Cassinadri, M. T.; Pezzotti, P.; Ajelli, M.; Rossi, P. G.; Merler, S.; Poletti, P.. - In: EPIDEMICS. - ISSN 1755-4365. - 44:(2023), pp. 100712-100712. [10.1016/j.epidem.2023.100712]
Molina Grané, C.; Mancuso, P.; Vicentini, M.; Venturelli, F.; Djuric, O.; Manica, M.; Guzzetta, G.; Marziano, V.; Zardini, A.; D'Andrea, V.; Trentini, F.; Bisaccia, E.; Larosa, E.; Cilloni, S.; Cassinadri, M. T.; Pezzotti, P.; Ajelli, M.; Rossi, P. G.; Merler, S.; Poletti, P.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1313546
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