Coordination of protein quality control processes across organelles is poorly understood. A study now shows that the cytosolic juxtanuclear quality control (JUNQ) and intranuclear quality control (INQ) compartments face each other on opposite sides of the nuclear envelope before their vacuolar degradation, promoting proteostasis.
A shared fate for nuclear and cytosolic inclusions / Alberti, Simon; Carra, Serena. - In: NATURE CELL BIOLOGY. - ISSN 1476-4679. - 25:5(2023), pp. 629-630. [10.1038/s41556-023-01121-z]
A shared fate for nuclear and cytosolic inclusions
Carra, Serena
2023
Abstract
Coordination of protein quality control processes across organelles is poorly understood. A study now shows that the cytosolic juxtanuclear quality control (JUNQ) and intranuclear quality control (INQ) compartments face each other on opposite sides of the nuclear envelope before their vacuolar degradation, promoting proteostasis.
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