Researchers, regulatory agencies, and the pharmaceutical industry are moving towards precision pharmacovigilance as a comprehensive framework for drug safety assessment, at the service of the individual patient, by clustering specific risk groups in different databases. This article explores its implementation by focusing on: (i) designing a new data collection infrastructure, (ii) exploring new computational methods suitable for drug safety data, and (iii) providing a computer-aided framework for distributed clinical decisions with the aim of compiling a personalized information leaflet with specific reference to a drug's risks and adverse drug reactions. These goals can be achieved by using 'smart hospitals' as the principal data sources and by employing methods of precision medicine and medical statistics to supplement current public health decisions.

A smart hospital-driven approach to precision pharmacovigilance / De Pretis, Francesco; van Gils, Mark; Forsberg, Markus M. - In: TRENDS IN PHARMACOLOGICAL SCIENCES. - ISSN 0165-6147. - 43:6(2022), pp. 473-481. [10.1016/j.tips.2022.03.009]

A smart hospital-driven approach to precision pharmacovigilance

De Pretis, Francesco;
2022

Abstract

Researchers, regulatory agencies, and the pharmaceutical industry are moving towards precision pharmacovigilance as a comprehensive framework for drug safety assessment, at the service of the individual patient, by clustering specific risk groups in different databases. This article explores its implementation by focusing on: (i) designing a new data collection infrastructure, (ii) exploring new computational methods suitable for drug safety data, and (iii) providing a computer-aided framework for distributed clinical decisions with the aim of compiling a personalized information leaflet with specific reference to a drug's risks and adverse drug reactions. These goals can be achieved by using 'smart hospitals' as the principal data sources and by employing methods of precision medicine and medical statistics to supplement current public health decisions.
2022
43
6
473
481
A smart hospital-driven approach to precision pharmacovigilance / De Pretis, Francesco; van Gils, Mark; Forsberg, Markus M. - In: TRENDS IN PHARMACOLOGICAL SCIENCES. - ISSN 0165-6147. - 43:6(2022), pp. 473-481. [10.1016/j.tips.2022.03.009]
De Pretis, Francesco; van Gils, Mark; Forsberg, Markus M
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1298711
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