: Vascular sequelae following (SARS-CoV-2 coronavirus disease) (COVID)-19 infection are considered as "Long Covid (LC)" disease, when occurring 12 weeks after the original infection. The paucity of specific data can be obviated by translating pathophysiological elements from the original Severe Acute Respiratory Syndrome-Corona Virus (SARS-CoV-2) infection (In a microcirculatory system, a first "endotheliitis," is often followed by production of "Neutrophil Extracellular Trap," and can evolve into a more complex leukocytoklastic-like and hyperimmune vasculitis. In medium/large-sized vessels, this corresponds to endothelial dysfunction, leading to an accelerated progression of pre-existing atherosclerotic plaques through an increased deposition of platelets, circulating inflammatory cells and proteins. Associated dysregulated immune and pro-coagulant conditions can directly cause thrombo-embolic arterial or venous complications. In order to implement appropriate treatment, physicians need to consider vascular pathologies observed after SARS-Cov-2 infections as possible "LC" disease.

Vascular "Long COVID": A New Vessel Disease? / Zanini, Giada; Selleri, Valentina; Roncati, Luca; Coppi, Francesca; Nasi, Milena; Farinetti, Alberto; Manenti, Antonio; Pinti, Marcello; Mattioli, Anna Vittoria. - In: ANGIOLOGY. - ISSN 0003-3197. - (2023), pp. 33197231153204-33197231153208. [10.1177/00033197231153204]

Vascular "Long COVID": A New Vessel Disease?

Zanini, Giada
Membro del Collaboration Group
;
Selleri, Valentina
Membro del Collaboration Group
;
Roncati, Luca
Membro del Collaboration Group
;
Coppi, Francesca
Membro del Collaboration Group
;
Nasi, Milena
Membro del Collaboration Group
;
Farinetti, Alberto
Membro del Collaboration Group
;
Manenti, Antonio
Membro del Collaboration Group
;
Pinti, Marcello
Membro del Collaboration Group
;
Mattioli, Anna Vittoria
Membro del Collaboration Group
2023-01-01

Abstract

: Vascular sequelae following (SARS-CoV-2 coronavirus disease) (COVID)-19 infection are considered as "Long Covid (LC)" disease, when occurring 12 weeks after the original infection. The paucity of specific data can be obviated by translating pathophysiological elements from the original Severe Acute Respiratory Syndrome-Corona Virus (SARS-CoV-2) infection (In a microcirculatory system, a first "endotheliitis," is often followed by production of "Neutrophil Extracellular Trap," and can evolve into a more complex leukocytoklastic-like and hyperimmune vasculitis. In medium/large-sized vessels, this corresponds to endothelial dysfunction, leading to an accelerated progression of pre-existing atherosclerotic plaques through an increased deposition of platelets, circulating inflammatory cells and proteins. Associated dysregulated immune and pro-coagulant conditions can directly cause thrombo-embolic arterial or venous complications. In order to implement appropriate treatment, physicians need to consider vascular pathologies observed after SARS-Cov-2 infections as possible "LC" disease.
33197231153204
33197231153208
Vascular "Long COVID": A New Vessel Disease? / Zanini, Giada; Selleri, Valentina; Roncati, Luca; Coppi, Francesca; Nasi, Milena; Farinetti, Alberto; Manenti, Antonio; Pinti, Marcello; Mattioli, Anna Vittoria. - In: ANGIOLOGY. - ISSN 0003-3197. - (2023), pp. 33197231153204-33197231153208. [10.1177/00033197231153204]
Zanini, Giada; Selleri, Valentina; Roncati, Luca; Coppi, Francesca; Nasi, Milena; Farinetti, Alberto; Manenti, Antonio; Pinti, Marcello; Mattioli, Anna Vittoria
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1295191
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