COPD is a chronic respiratory disease with prominent systemic consequences and comorbidities. While historically it has been characterized by airflow limitation, we now understand it as a multi-component disease with many clinical phenotypes, systemic manifestations, and associated co-morbidities. With this new and broader concept in mind, standard treatment of the respiratory disease with bronchodilators, antiinflammatory medications, and exacerbation management interventions may fall short in optimizing outcomes. This narrative review emphasizes the holistic treatment of the COPD patient, based on newly developed concepts of its pathogenesis, nature, and necessary comprehensive approaches to its therapy. The material in its four sections: 1) New Concepts of COPD; 2) Enhancing Outcomes in COPD; 3) Non-Pharmacologic Management of COPD; and 4) Optimizing Delivery of Care for COPD is not mean to be provide an exhaustive review of all aspects of COPD; rather, it presents what experts in the field consider novel and important in providing the right treatment for the right patient at the right time.
COPD: Providing the Right Treatment for the Right Patient at the Right Time / Agusti, Alvar; Ambrosino, Nicolino; Blackstock, Felicity; Bourbeau, Jean; Casaburi, Richard; Celli, Bartolome; Crouch, Rebecca; Dal Negro, Roberto; Dreher, Michael; Garvey, Christine; Gerardi, Daniel; Goldstein, Roger; Hanania, Nicola; Holland, Anne E.; Kaur, Antarpreet; Lareau, Suzanne; Lindenauer, Peter; Mannino, David; Make, Barry; Maltais, François; Marciniuk, Jeffrey; Meek, Paula; Morgan, Mike; Pepin, Jean-Louis; Reardon, Jane; Rochester, Carolyn; Singh, Sally; Spruit, Martijn; Steiner, Michael; Troosters, Thierry; Vitacca, Michele; Clini, Enrico; Jardim, Jose; Nici, Linda; Raskin, Jonathan; Zuwallack., Richard. - In: RESPIRATORY MEDICINE. - ISSN 1745-0454. - 207:(2023), pp. 1-25. [10.1016/j.rmed.2022.107041]
COPD: Providing the Right Treatment for the Right Patient at the Right Time.
Enrico Clini;
2023
Abstract
COPD is a chronic respiratory disease with prominent systemic consequences and comorbidities. While historically it has been characterized by airflow limitation, we now understand it as a multi-component disease with many clinical phenotypes, systemic manifestations, and associated co-morbidities. With this new and broader concept in mind, standard treatment of the respiratory disease with bronchodilators, antiinflammatory medications, and exacerbation management interventions may fall short in optimizing outcomes. This narrative review emphasizes the holistic treatment of the COPD patient, based on newly developed concepts of its pathogenesis, nature, and necessary comprehensive approaches to its therapy. The material in its four sections: 1) New Concepts of COPD; 2) Enhancing Outcomes in COPD; 3) Non-Pharmacologic Management of COPD; and 4) Optimizing Delivery of Care for COPD is not mean to be provide an exhaustive review of all aspects of COPD; rather, it presents what experts in the field consider novel and important in providing the right treatment for the right patient at the right time.File | Dimensione | Formato | |
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Zu Wallack (COPD- right patient right therapy- review 2023).pdf
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