Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL

Antic, D.; Milic, N.; Chatzikonstantinou, T.; Scarfo, L.; Otasevic, V.; Rajovic, N.; Allsup, D.; Alonso Cabrero, A.; Andres, M.; Baile Gonzales, M.; Capasso, A.; Collado, R.; Cordoba, R.; Cuellar-Garcia, C.; Correa, J. G.; De Paoli, L.; De Paolis, M. R.; Del Poeta, G.; Dimou, M.; Doubek, M.; Efstathopoulou, M.; El-Ashwah, S.; Enrico, A.; Espinet, B.; Farina, L.; Ferrari, A.; Foglietta, M.; Lopez-Garcia, A.; Garcia-Marco, J. A.; Garcia-Serra, R.; Gentile, M.; Gimeno, E.; Da Silva, M. G.; Gutwein, O.; Hakobyan, Y. K.; Herishanu, Y.; Hernandez-Rivas, J. A.; Herold, T.; Itchaki, G.; Jaksic, O.; Janssens, A.; Kalashnikova, O. B.; Kalicinska, E.; Kater, A. P.; Kersting, S.; Koren-Michowitz, M.; Labrador, J.; Lad, D.; Laurenti, L.; Fresa, A.; Levin, M. -D.; Mayor Bastida, C.; Malerba, L.; Marasca, R.; Marchetti, M.; Marquet, J.; Mihaljevic, B.; Milosevic, I.; Miras, F.; Morawska, M.; Motta, M.; Munir, T.; Murru, R.; Nunes, R.; Olivieri, J.; Pavlovsky, M. A.; Piskunova, I.; Popov, V. M.; Quaglia, F. M.; Quaresmini, G.; Reda, G.; Rigolin, G. M.; Shrestha, A.; Simkovic, M.; Smirnova, S.; Spacek, M.; Sportoletti, P.; Stanca, O.; Stavroyianni, N.; Te Raa, D.; Tomic, K.; Tonino, S.; Trentin, L.; Van Der Spek, E.; Van Gelder, M.; Varettoni, M.; Visentin, A.; Vitale, C.; Vukovic, V.; Wasik-Szczepanek, E.; Wrobel, T.; Segundo, L. Y. S.; Yassin, M.; Coscia, M.; Rambaldi, A.; Montserrat, E.; Foa, R.; Cuneo, A.; Carrier, M.; Ghia, P.; Stamatopoulos, K.

doi:10.1186/s13045-022-01333-0

Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to COVID-19 related poor outcomes, including thrombosis and death, due to the advanced age, the presence of comorbidities, and the disease and treatment-related immune deficiency. The aim of this study was to assess the risk of thrombosis and bleeding in patients with CLL affected by severe COVID-19.

Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL / Antic, D., Milic, N., Chatzikonstantinou, T., Scarfo, L., Otasevic, V., Rajovic, N., Allsup, D., Alonso Cabrero, A., Andres, M., Baile Gonzales, M., Capasso, A., Collado, R., Cordoba, R., Cuellar-Garcia, C., Correa, J.G., De Paoli, L., De Paolis, M.R., Del Poeta, G., Dimou, M., Doubek, M., et al.. - In: JOURNAL OF HEMATOLOGY & ONCOLOGY. - ISSN 1756-8722. - 15:1(2022), pp. 116-N/A. [10.1186/s13045-022-01333-0]