The hypersecretion of opioids is evaluated in hyperphagic obesity. The abnormal and persistent stimulation of β-Endorphin after glucose load (even after weight loss) suggests a direct involvement of endogenous opioids in the reward properties of food intake.
β-Endorphin and consummatory behaviors: The case of hyperphagic obesity / Facchinetti, Fabio. - (1990), p. 184. (Intervento presentato al convegno The International Narcotics Research Conference tenutosi a na nel 1989).