Donation after circulatory death (DCD) programs are expanding in Europe, in the attempt to expand donors pool. Even in controlled DCD donors, however, a protracted warm ischemia time occurring in the perimortem period might damage organs, making these unsuitable for transplantation. Implementing a strategy of extracorporeal interval support for organ retrieval (EISOR), a regional reperfusion with normothermic, oxygenated blood provides a physiologic environment allowing extensive assessment of potential grafts, and potentially promotes recovery of native function. Here we report the results of a multi-center retrospective cohort study including 29 Maastricht Category III controlled DCD donors undergoing extracorporeal support in a regional DCD/EISOR Training Center, and in the network of referring In-Training Centers, under the liaison of the regional Transplant Coordination Center during COVID-19 pandemic, between March 2020 and November 2021. The study aims to understand whether a mobile, experienced EISOR team implementing a consistent technique and sharing its equipe, expertise and equipment in a regional network of hospitals, might be effective and efficient in implementing the regional DCD program activity even in a highly stressed healthcare system.

Extracorporeal interval support for organ retrieval delivery regional experience with sharing equipe, equipment & expertise to increase conventionally defined as controlled donor pool in time of pandemic / Circelli, A.; Antonini, M. V.; Gamberini, E.; Nanni, A.; Benni, M.; Castioni, C. A.; Gordini, G.; Maitan, S.; Piccioni, F.; Tarantino, G.; Prugnoli, M.; Spiga, M.; Altini, M.; Di Benedetto, F.; Cescon, M.; Solli, P.; Catena, F.; Ercolani, G.; Russo, E.; Agnoletti, V.. - In: PERFUSION-UK. - ISSN 0267-6591. - 1(2022), pp. N/A-N/A. [10.1177/02676591221103535]

Extracorporeal interval support for organ retrieval delivery regional experience with sharing equipe, equipment & expertise to increase conventionally defined as controlled donor pool in time of pandemic

Di Benedetto F.;
2022

Abstract

Donation after circulatory death (DCD) programs are expanding in Europe, in the attempt to expand donors pool. Even in controlled DCD donors, however, a protracted warm ischemia time occurring in the perimortem period might damage organs, making these unsuitable for transplantation. Implementing a strategy of extracorporeal interval support for organ retrieval (EISOR), a regional reperfusion with normothermic, oxygenated blood provides a physiologic environment allowing extensive assessment of potential grafts, and potentially promotes recovery of native function. Here we report the results of a multi-center retrospective cohort study including 29 Maastricht Category III controlled DCD donors undergoing extracorporeal support in a regional DCD/EISOR Training Center, and in the network of referring In-Training Centers, under the liaison of the regional Transplant Coordination Center during COVID-19 pandemic, between March 2020 and November 2021. The study aims to understand whether a mobile, experienced EISOR team implementing a consistent technique and sharing its equipe, expertise and equipment in a regional network of hospitals, might be effective and efficient in implementing the regional DCD program activity even in a highly stressed healthcare system.
2022
1
N/A
N/A
Extracorporeal interval support for organ retrieval delivery regional experience with sharing equipe, equipment & expertise to increase conventionally defined as controlled donor pool in time of pandemic / Circelli, A.; Antonini, M. V.; Gamberini, E.; Nanni, A.; Benni, M.; Castioni, C. A.; Gordini, G.; Maitan, S.; Piccioni, F.; Tarantino, G.; Prugnoli, M.; Spiga, M.; Altini, M.; Di Benedetto, F.; Cescon, M.; Solli, P.; Catena, F.; Ercolani, G.; Russo, E.; Agnoletti, V.. - In: PERFUSION-UK. - ISSN 0267-6591. - 1(2022), pp. N/A-N/A. [10.1177/02676591221103535]
Circelli, A.; Antonini, M. V.; Gamberini, E.; Nanni, A.; Benni, M.; Castioni, C. A.; Gordini, G.; Maitan, S.; Piccioni, F.; Tarantino, G.; Prugnoli, M.; Spiga, M.; Altini, M.; Di Benedetto, F.; Cescon, M.; Solli, P.; Catena, F.; Ercolani, G.; Russo, E.; Agnoletti, V.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1286469
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