□Objectives. To evaluate healing of cystic lesions in human jawbone filled with autologous bone or PLA-PGA copolymer (Fisiograft ®), by means of clinical, radiological and histological methods. □Material and Methods. After informed consent eight male patients underwent surgical treatment of dental cysts caused by teeth where endodontic treatment failed. Patients were randomly divided into 2 groups: the first (control group) received an autologous bone graft while the second (treatment group) was treated by copolymer with a follow-up of 4 months. □Results. Autologous bone provided a lightly better clinical and radiological (area, diameters, gray level) outcome without statistically significant differences. Bone activities were enhanced in sites treated with copolymer, whereas a steady-state was observed with autologous bone. The amount of bone (TBV) was similar in both groups (m ∼ 16,5%). □Conclusions. Our results indicate that best outcomes are achieved using autologous bone graft, but good results can also follow the use of copolymer to promote healing of severe bone defects. Additionally, copolymer is easy to handle and does not require a secondary donor site.

Comparative study on bone regeneration of cystic lesions / Bertoldi, C.; Zaffe, D.; Lucchi, A.; Consolo, U.. - In: ITALIAN ORAL SURGERY. - ISSN 1827-2452. - 8:3(2009), pp. 145-152.

Comparative study on bone regeneration of cystic lesions

Bertoldi C.;Zaffe D.;Consolo U.
2009

Abstract

□Objectives. To evaluate healing of cystic lesions in human jawbone filled with autologous bone or PLA-PGA copolymer (Fisiograft ®), by means of clinical, radiological and histological methods. □Material and Methods. After informed consent eight male patients underwent surgical treatment of dental cysts caused by teeth where endodontic treatment failed. Patients were randomly divided into 2 groups: the first (control group) received an autologous bone graft while the second (treatment group) was treated by copolymer with a follow-up of 4 months. □Results. Autologous bone provided a lightly better clinical and radiological (area, diameters, gray level) outcome without statistically significant differences. Bone activities were enhanced in sites treated with copolymer, whereas a steady-state was observed with autologous bone. The amount of bone (TBV) was similar in both groups (m ∼ 16,5%). □Conclusions. Our results indicate that best outcomes are achieved using autologous bone graft, but good results can also follow the use of copolymer to promote healing of severe bone defects. Additionally, copolymer is easy to handle and does not require a secondary donor site.
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Comparative study on bone regeneration of cystic lesions / Bertoldi, C.; Zaffe, D.; Lucchi, A.; Consolo, U.. - In: ITALIAN ORAL SURGERY. - ISSN 1827-2452. - 8:3(2009), pp. 145-152.
Bertoldi, C.; Zaffe, D.; Lucchi, A.; Consolo, U.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1286437
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