Introduction: Metastatic spread in invasive lobular carcinoma (ILC) of breast mainly occurs in bones, gynecological organs, peritoneum, retroperitoneum, and gastrointestinal (GI) tract. Metastases to the GI tract may arise many years after initial diagnosis and can affect the tract from the tongue to the anus, stomach being the most commonly involved site. Clinical presentations are predominantly nonspecific, and rarely asymptomatic. CEA, CA 15-3, and CA 19-9 may be informative for symptomatic patients who have had a previous history of breast cancer. Case presentation: We introduce the case of asymptomatic colonic metastasis from breast carcinoma in a 67-year-old woman followed-up for Luminal A ILC. Diagnosis was performed through positron emission tomography/computed tomography (PET/CT) scan and contrast-enhancement spectral mammography (CESM), steering endoscopist to spot the involved intestinal tract and in ruling out further dissemination in the breast parenchyma. Conclusion: In colonic metastases, tumor markers might not be totally reliable. In asymptomatic cases, clinical conditions might be underappreciated, missing local or distant recurrence. CT and PET/CT scan might be useful in diagnosing small volume diseases, and steering endoscopist toward GI metastasis originating from the breast. CESM represents a tolerable and feasible tool that rules out multicentricity and multifocality of breast localization. Moreover, particular patients could tolerate it better than magnetic resonance imaging (MRI).

Colonic metastasis from breast carcinoma detection by CESM and PET/CT: A case report / Falco, G.; Mele, S.; Zizzo, M.; Di Grezia, G.; Cecinato, P.; Besutti, G.; Coiro, S.; Gatta, G.; Vacondio, R.; Ferrari, G.. - In: MEDICINE. - ISSN 0025-7974. - 97:21(2018), pp. e10888-N/A. [10.1097/MD.0000000000010888]

Colonic metastasis from breast carcinoma detection by CESM and PET/CT: A case report

Mele S.;Zizzo M.;Di Grezia G.;Besutti G.;
2018-01-01

Abstract

Introduction: Metastatic spread in invasive lobular carcinoma (ILC) of breast mainly occurs in bones, gynecological organs, peritoneum, retroperitoneum, and gastrointestinal (GI) tract. Metastases to the GI tract may arise many years after initial diagnosis and can affect the tract from the tongue to the anus, stomach being the most commonly involved site. Clinical presentations are predominantly nonspecific, and rarely asymptomatic. CEA, CA 15-3, and CA 19-9 may be informative for symptomatic patients who have had a previous history of breast cancer. Case presentation: We introduce the case of asymptomatic colonic metastasis from breast carcinoma in a 67-year-old woman followed-up for Luminal A ILC. Diagnosis was performed through positron emission tomography/computed tomography (PET/CT) scan and contrast-enhancement spectral mammography (CESM), steering endoscopist to spot the involved intestinal tract and in ruling out further dissemination in the breast parenchyma. Conclusion: In colonic metastases, tumor markers might not be totally reliable. In asymptomatic cases, clinical conditions might be underappreciated, missing local or distant recurrence. CT and PET/CT scan might be useful in diagnosing small volume diseases, and steering endoscopist toward GI metastasis originating from the breast. CESM represents a tolerable and feasible tool that rules out multicentricity and multifocality of breast localization. Moreover, particular patients could tolerate it better than magnetic resonance imaging (MRI).
97
21
e10888
N/A
Colonic metastasis from breast carcinoma detection by CESM and PET/CT: A case report / Falco, G.; Mele, S.; Zizzo, M.; Di Grezia, G.; Cecinato, P.; Besutti, G.; Coiro, S.; Gatta, G.; Vacondio, R.; Ferrari, G.. - In: MEDICINE. - ISSN 0025-7974. - 97:21(2018), pp. e10888-N/A. [10.1097/MD.0000000000010888]
Falco, G.; Mele, S.; Zizzo, M.; Di Grezia, G.; Cecinato, P.; Besutti, G.; Coiro, S.; Gatta, G.; Vacondio, R.; Ferrari, G.
File in questo prodotto:
File Dimensione Formato  
Colonic_metastasis_from_breast_carcinoma_detection.74.pdf

Open access

Tipologia: Versione pubblicata dall'editore
Dimensione 583.19 kB
Formato Adobe PDF
583.19 kB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1281557
Citazioni
  • ???jsp.display-item.citation.pmc??? 7
  • Scopus 11
  • ???jsp.display-item.citation.isi??? 7
social impact