Neurotoxicology is a specialty that aims to understand and explain the impact of chemicals, xenobiotics and physical conditions on nervous system function throughout the life span. Herein, we point to the need for integration of novel translational bioinformatics and chemo-informatics approaches, such as machine learning (ML) and artificial intelligence (AI) to the discipline. Specifically, we advance the notion that AI and ML will be helpful in identifying neurotoxic signatures, provide reliable data in predicting neurotoxicity in the context of genetic variability, and improve the understanding of neurotoxic outcomes associated with exposures to mixtures, to name a few.

Leveraging artificial intelligence to advance the understanding of chemical neurotoxicity / Aschner, M.; Mesnage, R.; Docea, A. O.; Paoliello, M. M. B.; Tsatsakis, A.; Giannakakis, G.; Papadakis, G. Z.; Vinceti, S. R.; Santamaria, A.; Skalny, A. V.; Tinkov, A. A.. - In: NEUROTOXICOLOGY. - ISSN 0161-813X. - 89:(2022), pp. 9-11. [10.1016/j.neuro.2021.12.007]

Leveraging artificial intelligence to advance the understanding of chemical neurotoxicity

Vinceti S. R.;
2022

Abstract

Neurotoxicology is a specialty that aims to understand and explain the impact of chemicals, xenobiotics and physical conditions on nervous system function throughout the life span. Herein, we point to the need for integration of novel translational bioinformatics and chemo-informatics approaches, such as machine learning (ML) and artificial intelligence (AI) to the discipline. Specifically, we advance the notion that AI and ML will be helpful in identifying neurotoxic signatures, provide reliable data in predicting neurotoxicity in the context of genetic variability, and improve the understanding of neurotoxic outcomes associated with exposures to mixtures, to name a few.
2022
89
9
11
Leveraging artificial intelligence to advance the understanding of chemical neurotoxicity / Aschner, M.; Mesnage, R.; Docea, A. O.; Paoliello, M. M. B.; Tsatsakis, A.; Giannakakis, G.; Papadakis, G. Z.; Vinceti, S. R.; Santamaria, A.; Skalny, A. V.; Tinkov, A. A.. - In: NEUROTOXICOLOGY. - ISSN 0161-813X. - 89:(2022), pp. 9-11. [10.1016/j.neuro.2021.12.007]
Aschner, M.; Mesnage, R.; Docea, A. O.; Paoliello, M. M. B.; Tsatsakis, A.; Giannakakis, G.; Papadakis, G. Z.; Vinceti, S. R.; Santamaria, A.; Skalny,...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1274446
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