This retrospective study was carried out to assess the prognostic value of three classification systems used for staging cutaneous head and neck malig- nant melanoma (CHNME). Fifty-three patients with histologically proven CHNME were analyzed. Thirty patients were never treated before admis- sion, whereas 23 (43.4%) had a second radical re- section of the primary tumor location, 9 (17%) had neck nodes, none had distant metastasis, and all had a minimum of 5 years of follow-up. Results show that T-stage is the most important clinical prognostic parameter, whereas Clark’s and Breslow’s classifications have lower impact in defining prog- nosis. Sites of primary tumor determines different clinical outcomes, but this does not reach statistically significant values. A second surgery on the primary tumor location is possible and is effective toward survival. No statistical differences were noted be- tween the previously untreated and treated groups. Neck nodes have to be removed with neck dissection, and this regimen can improve the clinical outcome; however, only 40% of neck positive patients survive more than 5 years.

Comparison Among Clark’s, Breslow’s, and TNM Classifications for Cutaneous Head and Neck Malignant Melanoma / Morselli, Paolo; L., Masciotra; Pinto, Valentina; I., Zollino; G., Brunelli; F., Carinci. - In: THE JOURNAL OF CRANIOFACIAL SURGERY. - ISSN 1049-2275. - 18:6(2007), pp. 1353-1358. [10.1097/scs.0b013e3180534453]

Comparison Among Clark’s, Breslow’s, and TNM Classifications for Cutaneous Head and Neck Malignant Melanoma

PINTO, VALENTINA;
2007

Abstract

This retrospective study was carried out to assess the prognostic value of three classification systems used for staging cutaneous head and neck malig- nant melanoma (CHNME). Fifty-three patients with histologically proven CHNME were analyzed. Thirty patients were never treated before admis- sion, whereas 23 (43.4%) had a second radical re- section of the primary tumor location, 9 (17%) had neck nodes, none had distant metastasis, and all had a minimum of 5 years of follow-up. Results show that T-stage is the most important clinical prognostic parameter, whereas Clark’s and Breslow’s classifications have lower impact in defining prog- nosis. Sites of primary tumor determines different clinical outcomes, but this does not reach statistically significant values. A second surgery on the primary tumor location is possible and is effective toward survival. No statistical differences were noted be- tween the previously untreated and treated groups. Neck nodes have to be removed with neck dissection, and this regimen can improve the clinical outcome; however, only 40% of neck positive patients survive more than 5 years.
2007
18
6
1353
1358
Comparison Among Clark’s, Breslow’s, and TNM Classifications for Cutaneous Head and Neck Malignant Melanoma / Morselli, Paolo; L., Masciotra; Pinto, Valentina; I., Zollino; G., Brunelli; F., Carinci. - In: THE JOURNAL OF CRANIOFACIAL SURGERY. - ISSN 1049-2275. - 18:6(2007), pp. 1353-1358. [10.1097/scs.0b013e3180534453]
Morselli, Paolo; L., Masciotra; Pinto, Valentina; I., Zollino; G., Brunelli; F., Carinci
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1264804
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