We report the results of a study on the search for herpesvirus DNA in liver biopsy from patients with chronic hepatitis C and from a control group without hepatitis. Thirty-four liver samples from hepatitis C patients were examined, 12 of which (35.3%) were positive for at least one herpesvirus DNA, whereas among the 19 control liver samples only 2 were positive (10.5%; p= 0.049). Liver biopsies from 7 patients, 3 with acute hepatitis of unknown origin, 3 with non alcoholic steatoheapatitis and 1 with autoimmune hepatitis were investigated too and three positive samples were found. The prevalence of herpesvirus DNA higher in patients with hepatitis C than in individuals without hepatitis is discussed and the possible influence of herpesviruses both on the clinical course and on the therapy of hepatitis C is considered.
Prevalenza degli herpesvirus nel tessuto epatico da soggetti con epatite C / Cermelli, C.; Concari, M.; Pietrosemoli, P.; Meacci, M.; Sabbatini, A. M. T.; Loria, P.; Divincenzo, A.; Portolani, M.. - In: L'IGIENE MODERNA. - ISSN 0019-1655. - 112:1(1999), pp. 121-133.
Prevalenza degli herpesvirus nel tessuto epatico da soggetti con epatite C
Cermelli C.;Sabbatini A. M. T.;Loria P.;Portolani M.
1999
Abstract
We report the results of a study on the search for herpesvirus DNA in liver biopsy from patients with chronic hepatitis C and from a control group without hepatitis. Thirty-four liver samples from hepatitis C patients were examined, 12 of which (35.3%) were positive for at least one herpesvirus DNA, whereas among the 19 control liver samples only 2 were positive (10.5%; p= 0.049). Liver biopsies from 7 patients, 3 with acute hepatitis of unknown origin, 3 with non alcoholic steatoheapatitis and 1 with autoimmune hepatitis were investigated too and three positive samples were found. The prevalence of herpesvirus DNA higher in patients with hepatitis C than in individuals without hepatitis is discussed and the possible influence of herpesviruses both on the clinical course and on the therapy of hepatitis C is considered.
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
