Systemic sclerosis is a connective tissue disease with cutaneous involvement. Clinical manifestations result from the balance of inflammations/autoimmunity process and fibrogenesis. Patients suffer from skin ulcers, non-ulcerative lesions including digital pitting scars, telangiectasias, subungual hyperkeratosis, abrasions, fissures, and subcutaneous calcinosis. A review about the pathophysiology of the disease, the physical examination of the patients, the instrumental assessment, and possible treatments is performed.

Systemic sclerosis cutaneous expression: Management of skin fibrosis and digital ulcers / Starnoni, M.; Pappalardo, M.; Spinella, A.; Testoni, S.; Lattanzi, M.; Femino, R.; De Santis, G.; Salvarani, C.; Giuggioli, D.. - In: ANNALS OF MEDICINE AND SURGERY. - ISSN 2049-0801. - 71:(2021), pp. 1-6. [10.1016/j.amsu.2021.102984]

Systemic sclerosis cutaneous expression: Management of skin fibrosis and digital ulcers

Starnoni M.;Pappalardo M.;Spinella A.;Testoni S.;Lattanzi M.;De Santis G.;Salvarani C.;Giuggioli D.
2021

Abstract

Systemic sclerosis is a connective tissue disease with cutaneous involvement. Clinical manifestations result from the balance of inflammations/autoimmunity process and fibrogenesis. Patients suffer from skin ulcers, non-ulcerative lesions including digital pitting scars, telangiectasias, subungual hyperkeratosis, abrasions, fissures, and subcutaneous calcinosis. A review about the pathophysiology of the disease, the physical examination of the patients, the instrumental assessment, and possible treatments is performed.
2021
71
1
6
Systemic sclerosis cutaneous expression: Management of skin fibrosis and digital ulcers / Starnoni, M.; Pappalardo, M.; Spinella, A.; Testoni, S.; Lattanzi, M.; Femino, R.; De Santis, G.; Salvarani, C.; Giuggioli, D.. - In: ANNALS OF MEDICINE AND SURGERY. - ISSN 2049-0801. - 71:(2021), pp. 1-6. [10.1016/j.amsu.2021.102984]
Starnoni, M.; Pappalardo, M.; Spinella, A.; Testoni, S.; Lattanzi, M.; Femino, R.; De Santis, G.; Salvarani, C.; Giuggioli, D.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1256879
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