Background: Sodium prescription in patients with intradialytic hypotension remains a challenge for the attending nephrologist as it increases dialysate conductivity in hypotension-prone patients, thereby adding to dietary sodium. Methods: New sodium prescription strategies are now available, including the use of a mathematical model to compute the sodium mass to be removed during dialysis as a physiological controller. Results: This review describes the sodium load of patients with end-stage renal disease on chronic hemodialysis and discusses two strategies to remove excess sodium in patients prone to intradialytic hypotension, namely Profiled hemodialysis and the HFR Aequilibrium System. Conclusion: The Profiled hemodialysis and Aequilibrium System trials both proved effective in counteracting intradialytic hypotension.
Sodium Prescription in the Prevention of Intradialytic Hypotension: New Insights into an Old Concept? / Donati, G; Ursino, M; Spazzoli, A; Natali, N; Schillaci, S; Conte, D; Angeletti, A; Croci Chiocchini, Al; Capelli, I; Baraldi, O; La Manna, G. - In: BLOOD PURIFICATION. - ISSN 0253-5068. - 45:1-3(2018), pp. 61-70. [10.1159/000480221]
Sodium Prescription in the Prevention of Intradialytic Hypotension: New Insights into an Old Concept?
Donati G;
2018
Abstract
Background: Sodium prescription in patients with intradialytic hypotension remains a challenge for the attending nephrologist as it increases dialysate conductivity in hypotension-prone patients, thereby adding to dietary sodium. Methods: New sodium prescription strategies are now available, including the use of a mathematical model to compute the sodium mass to be removed during dialysis as a physiological controller. Results: This review describes the sodium load of patients with end-stage renal disease on chronic hemodialysis and discusses two strategies to remove excess sodium in patients prone to intradialytic hypotension, namely Profiled hemodialysis and the HFR Aequilibrium System. Conclusion: The Profiled hemodialysis and Aequilibrium System trials both proved effective in counteracting intradialytic hypotension.
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