Background: Cardiac implantable electronic device (CIED) implantation rates as well as the clinical and procedural characteristics and outcomes in patients with known active coronavirus disease 2019 (COVID-19) are unknown. Objective: The purpose of this study was to gather information regarding CIED procedures during active COVID-19, performed with personal protective equipment, based on an international survey. Methods: Fifty-three centers from 13 countries across 4 continents provided information on 166 patients with known active COVID-19 who underwent a CIED procedure. Results: The CIED procedure rate in 133,655 hospitalized COVID-19 patients ranged from 0 to 16.2 per 1000 patients (P <.001). Most devices were implanted due to high-degree/complete atrioventricular block (112 [67.5%]) or sick sinus syndrome (31 [18.7%]). Of the 166 patients in the study survey, the 30-day complication rate was 13.9% and the 180-day mortality rate was 9.6%. One patient had a fatal outcome as a direct result of the procedure. Differences in patient and procedural characteristics and outcomes were found between Europe and North America. An older population (76.6 vs 66 years; P <.001) with a nonsignificant higher complication rate (16.5% vs 7.7%; P = .2) was observed in Europe vs North America, whereas higher rates of critically ill patients (33.3% vs 3.3%; P <.001) and mortality (26.9% vs 5%; P = .002) were observed in North America vs Europe. Conclusion: CIED procedure rates during known active COVID-19 disease varied greatly, from 0 to 16.2 per 1000 hospitalized COVID-19 patients worldwide. Patients with active COVID-19 infection who underwent CIED implantation had high complication and mortality rates. Operators should take these risks into consideration before proceeding with CIED implantation in active COVID-19 patients.

Implantation of cardiac electronic devices in active COVID-19 patients: Results from an international survey / Tovia-Brodie, Oholi; Acha, Moshe Rav; Belhassen, Bernard; Gasperetti, Alessio; Schiavone, Marco; Forleo, Giovanni Battista; Guevara-Valdivia, Milton E; Ruiz, David Valdeolivar; Lellouche, Nicolas; Hamon, David; Castagno, Davide; Bellettini, Matteo; De Ferrari, Gaetano M; Laredo, Mikael; Carvès, Jean-Baptiste; Ignatiuk, Barbara; Pasquetto, Giampaolo; De Filippo, Paolo; Malanchini, Giovanni; Pavri, Behzad B; Raphael, Craig; Rivetti, Luigi; Mantovan, Roberto; Chinitz, Jason; Harding, Melissa; Boriani, Giuseppe; Casali, Edoardo; Wan, Elaine Y; Biviano, Angelo; Macias, Carlos; Havranek, Stepan; Lazzerini, Pietro Enea; Canu, Antonio M; Zardini, Marco; Conte, Giulio; Cano, Óscar; Casella, Michela; Rudic, Boris; Omelchenko, Alexander; Mathuria, Nilesh; Upadhyay, Gaurav A; Danon, Asaf; Schwartz, Arie Lorin; Maury, Philippe; Nakahara, Shiro; Goldenberg, Gustavo; Schaerli, Nicolas; Bereza, Sergiy; Auricchio, Angelo; Glikson, Michael; Michowitz, Yoav. - In: HEART RHYTHM. - ISSN 1547-5271. - 19:2(2021), pp. 206-216. [10.1016/j.hrthm.2021.10.020]

Implantation of cardiac electronic devices in active COVID-19 patients: Results from an international survey

Boriani, Giuseppe;Casali, Edoardo;
2021

Abstract

Background: Cardiac implantable electronic device (CIED) implantation rates as well as the clinical and procedural characteristics and outcomes in patients with known active coronavirus disease 2019 (COVID-19) are unknown. Objective: The purpose of this study was to gather information regarding CIED procedures during active COVID-19, performed with personal protective equipment, based on an international survey. Methods: Fifty-three centers from 13 countries across 4 continents provided information on 166 patients with known active COVID-19 who underwent a CIED procedure. Results: The CIED procedure rate in 133,655 hospitalized COVID-19 patients ranged from 0 to 16.2 per 1000 patients (P <.001). Most devices were implanted due to high-degree/complete atrioventricular block (112 [67.5%]) or sick sinus syndrome (31 [18.7%]). Of the 166 patients in the study survey, the 30-day complication rate was 13.9% and the 180-day mortality rate was 9.6%. One patient had a fatal outcome as a direct result of the procedure. Differences in patient and procedural characteristics and outcomes were found between Europe and North America. An older population (76.6 vs 66 years; P <.001) with a nonsignificant higher complication rate (16.5% vs 7.7%; P = .2) was observed in Europe vs North America, whereas higher rates of critically ill patients (33.3% vs 3.3%; P <.001) and mortality (26.9% vs 5%; P = .002) were observed in North America vs Europe. Conclusion: CIED procedure rates during known active COVID-19 disease varied greatly, from 0 to 16.2 per 1000 hospitalized COVID-19 patients worldwide. Patients with active COVID-19 infection who underwent CIED implantation had high complication and mortality rates. Operators should take these risks into consideration before proceeding with CIED implantation in active COVID-19 patients.
2021
19
2
206
216
Implantation of cardiac electronic devices in active COVID-19 patients: Results from an international survey / Tovia-Brodie, Oholi; Acha, Moshe Rav; Belhassen, Bernard; Gasperetti, Alessio; Schiavone, Marco; Forleo, Giovanni Battista; Guevara-Valdivia, Milton E; Ruiz, David Valdeolivar; Lellouche, Nicolas; Hamon, David; Castagno, Davide; Bellettini, Matteo; De Ferrari, Gaetano M; Laredo, Mikael; Carvès, Jean-Baptiste; Ignatiuk, Barbara; Pasquetto, Giampaolo; De Filippo, Paolo; Malanchini, Giovanni; Pavri, Behzad B; Raphael, Craig; Rivetti, Luigi; Mantovan, Roberto; Chinitz, Jason; Harding, Melissa; Boriani, Giuseppe; Casali, Edoardo; Wan, Elaine Y; Biviano, Angelo; Macias, Carlos; Havranek, Stepan; Lazzerini, Pietro Enea; Canu, Antonio M; Zardini, Marco; Conte, Giulio; Cano, Óscar; Casella, Michela; Rudic, Boris; Omelchenko, Alexander; Mathuria, Nilesh; Upadhyay, Gaurav A; Danon, Asaf; Schwartz, Arie Lorin; Maury, Philippe; Nakahara, Shiro; Goldenberg, Gustavo; Schaerli, Nicolas; Bereza, Sergiy; Auricchio, Angelo; Glikson, Michael; Michowitz, Yoav. - In: HEART RHYTHM. - ISSN 1547-5271. - 19:2(2021), pp. 206-216. [10.1016/j.hrthm.2021.10.020]
Tovia-Brodie, Oholi; Acha, Moshe Rav; Belhassen, Bernard; Gasperetti, Alessio; Schiavone, Marco; Forleo, Giovanni Battista; Guevara-Valdivia, Milton E; Ruiz, David Valdeolivar; Lellouche, Nicolas; Hamon, David; Castagno, Davide; Bellettini, Matteo; De Ferrari, Gaetano M; Laredo, Mikael; Carvès, Jean-Baptiste; Ignatiuk, Barbara; Pasquetto, Giampaolo; De Filippo, Paolo; Malanchini, Giovanni; Pavri, Behzad B; Raphael, Craig; Rivetti, Luigi; Mantovan, Roberto; Chinitz, Jason; Harding, Melissa; Boriani, Giuseppe; Casali, Edoardo; Wan, Elaine Y; Biviano, Angelo; Macias, Carlos; Havranek, Stepan; Lazzerini, Pietro Enea; Canu, Antonio M; Zardini, Marco; Conte, Giulio; Cano, Óscar; Casella, Michela; Rudic, Boris; Omelchenko, Alexander; Mathuria, Nilesh; Upadhyay, Gaurav A; Danon, Asaf; Schwartz, Arie Lorin; Maury, Philippe; Nakahara, Shiro; Goldenberg, Gustavo; Schaerli, Nicolas; Bereza, Sergiy; Auricchio, Angelo; Glikson, Michael; Michowitz, Yoav
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