Only a third of patients with eosinophilic granulomatosis with polyangiitis (EGPA) are ANCA-positive, mainly directed against MPO. ANCA directed against PR3 are rarely found in EGPA. We aimed to examine the significance of PR3-ANCA in EGPA.
Significance of PR3-ANCA positivity in eosinophilic granulomatosis with polyangiitis (Churg-Strauss) / Papo, M., Sinico, R.A., Teixeira, V., Venhoff, N., Urban, M., Iudici, M., Mahrhold, J., Locatelli, F., Cassone, G., Schiavon, F., Seeliger, B., Neumann, T., Kroegel, C., Groh, M., Marvisi, C., Samson, M., Barba, T., Jayne, D., Troilo, A., Thiel, J., et al.. - In: RHEUMATOLOGY. - ISSN 1462-0324. - 60:9(2021), pp. 4355-4360. [10.1093/rheumatology/keaa805]
Significance of PR3-ANCA positivity in eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
Cassone, Giulia;Marvisi, Chiara;Salvarani, Carlo;
2021
Abstract
Only a third of patients with eosinophilic granulomatosis with polyangiitis (EGPA) are ANCA-positive, mainly directed against MPO. ANCA directed against PR3 are rarely found in EGPA. We aimed to examine the significance of PR3-ANCA in EGPA.
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