We report preliminary results of a procedure to obtain averaged maps of functional activity relative to several rat brains as well as between-groups difference maps. Functional maps are created using the 2-deoxyglucose method. Due to the variability in size, shape and location of structures between brains we have applied a non-linear deformation algorithm under landmark-driven constrains to obtain the matching of the 3-D reconstructed functional volumes. A volume obtained from images of histological sections is taken as reference atlas for the fitting procedure.
3-D Matching for interbrain functional imaging comparisons in rats / Baraldi, P.; Prandini, A.; Marini, M.; Porro, C. A.; Tedeschi, P.. - 15:1(1993), pp. 481-482. (Intervento presentato al convegno Proceedings of the 15th Annual International Conference of the IEEE Engineering in Medicine and Biology Society tenutosi a San Diego, CA, USA, nel 1993).