Converging lines of evidence point to the existence of immune dysfunction in autism spectrum disorder (ASD), which could directly affect several key neurodevelopmental processes. Previous studies have shown higher cytokine levels in patients with autism compared with matched controls or subjects with other developmental disorders. In the current study, we used plasma-cytokine profiling for 25 discordant sibling pairs to evaluate whether these alterations occur within families with ASD.
Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder / Napolioni, Valerio; Ober-Reynolds, Benjamin; Szelinger, Szabolcs; Corneveaux, Jason J; Pawlowski, Traci; Ober-Reynolds, Sharman; Kirwan, Janet; Persico, Antonio M; Melmed, Raun D; Craig, David W; Smith, Christopher J; Huentelman, Matthew J. - In: JOURNAL OF NEUROINFLAMMATION. - ISSN 1742-2094. - 10:(2013), pp. 38-49. [10.1186/1742-2094-10-38]
Plasma cytokine profiling in sibling pairs discordant for autism spectrum disorder
Persico, Antonio M;
2013
Abstract
Converging lines of evidence point to the existence of immune dysfunction in autism spectrum disorder (ASD), which could directly affect several key neurodevelopmental processes. Previous studies have shown higher cytokine levels in patients with autism compared with matched controls or subjects with other developmental disorders. In the current study, we used plasma-cytokine profiling for 25 discordant sibling pairs to evaluate whether these alterations occur within families with ASD.
| File | Dimensione | Formato | |
|---|---|---|---|
|
Cytokines_Napolioni_2013.pdf
Open access
Tipologia:
Versione pubblicata dall'editore
Dimensione
1.31 MB
Formato
Adobe PDF
|
1.31 MB | Adobe PDF | Visualizza/Apri |
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
