From invertebrates to humans, serotonin (5-HT) exerts structural effects especially during development. The 5-HT transporter (SERT) directly regulates these effects by maintaining extracellular 5-HT concentrations within a physiological range and possibly by modulating the intracellular redox state of the cell. This chapter addresses 5-HT trophic effects on developing neural and non-neural mammalian cells, and summarizes SERT roles in 5HT-mediated structural effects from basic neurodevelopment to human teratology.

Developmental roles of the serotonin transporter / Persico, A. M.. - (2010), pp. 78-104. [10.1017/CBO9780511729935.004]

Developmental roles of the serotonin transporter

Persico A. M.
2010

Abstract

From invertebrates to humans, serotonin (5-HT) exerts structural effects especially during development. The 5-HT transporter (SERT) directly regulates these effects by maintaining extracellular 5-HT concentrations within a physiological range and possibly by modulating the intracellular redox state of the cell. This chapter addresses 5-HT trophic effects on developing neural and non-neural mammalian cells, and summarizes SERT roles in 5HT-mediated structural effects from basic neurodevelopment to human teratology.
2010
Experimental Models in Serotonin Transporter Research
Kalueff A.V. LaPort J.L.
978-0-521-51487-3
Cambridge University Press
REGNO UNITO DI GRAN BRETAGNA
Developmental roles of the serotonin transporter / Persico, A. M.. - (2010), pp. 78-104. [10.1017/CBO9780511729935.004]
Persico, A. M.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1250863
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