IMPORTANCE Nested melanoma of the elderly is a newly identified histopathologic variant of superficial spreading melanoma, characterized by intraepidermal large nests. However, the clinical, dermoscopic, and confocal aspects have been depicted only partially. OBSERVATIONS In our cases series, nested melanoma was a flat, irregularly shaped lesion with variably pigmented and irregularly distributed globules on dermoscopic examination. Confocal microscopy revealed the presence of a "clod" pattern made of large compact nests with variable atypia. These findings correlated well with histopathologic features. CONCLUSIONS AND RELEVANCE Nested melanoma of the elderly should be included in the differential diagnosis when a flat pigmented lesion, showing dermoscopically an irregular globular pattern, is seen in a patient older than 60 years.

Dermoscopy and confocal microscopy of nested melanoma of the elderly recognizing a newly defined entity / Longo, C.; Zalaudek, I.; Piana, S.; Pellacani, G.; Lallas, A.; Reggiani, C.; Argenziano, G.. - In: JAMA DERMATOLOGY. - ISSN 2168-6068. - 149:8(2013), pp. 941-945. [10.1001/jamadermatol.2013.321]

Dermoscopy and confocal microscopy of nested melanoma of the elderly recognizing a newly defined entity

Longo C.;Pellacani G.;
2013

Abstract

IMPORTANCE Nested melanoma of the elderly is a newly identified histopathologic variant of superficial spreading melanoma, characterized by intraepidermal large nests. However, the clinical, dermoscopic, and confocal aspects have been depicted only partially. OBSERVATIONS In our cases series, nested melanoma was a flat, irregularly shaped lesion with variably pigmented and irregularly distributed globules on dermoscopic examination. Confocal microscopy revealed the presence of a "clod" pattern made of large compact nests with variable atypia. These findings correlated well with histopathologic features. CONCLUSIONS AND RELEVANCE Nested melanoma of the elderly should be included in the differential diagnosis when a flat pigmented lesion, showing dermoscopically an irregular globular pattern, is seen in a patient older than 60 years.
2013
149
8
941
945
Dermoscopy and confocal microscopy of nested melanoma of the elderly recognizing a newly defined entity / Longo, C.; Zalaudek, I.; Piana, S.; Pellacani, G.; Lallas, A.; Reggiani, C.; Argenziano, G.. - In: JAMA DERMATOLOGY. - ISSN 2168-6068. - 149:8(2013), pp. 941-945. [10.1001/jamadermatol.2013.321]
Longo, C.; Zalaudek, I.; Piana, S.; Pellacani, G.; Lallas, A.; Reggiani, C.; Argenziano, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1249792
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