Purpose: We report a case of a patient with a known hereditary spherocytosis who developed a bilateral macular hemorrhage in concurrence with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related respiratory syndrome. Observations: Blood tests showed severe hemolytic anemia. Interestingly, the peripheral blood smear demonstrated a mixed pathogenesis of the hemolytic process (cold-agglutinin-mediated and non-immune-mediated due to spherocytosis). Conclusions and Importance: We argue that SARS-CoV-2 could have triggered the hemolytic process, which led to retinal hemorrhages due to endothelial anoxia from the low oxygen carrying capacity.
Bilateral macular hemorrhage in a patient with COVID-19 / D'Aloisio, R.; Nasillo, V.; Gironi, M.; Mastropasqua, R.. - In: AMERICAN JOURNAL OF OPHTHALMOLOGY. CASE REPORTS. - ISSN 2451-9936. - 20:(2020), pp. N/A-N/A. [10.1016/j.ajoc.2020.100958]
Bilateral macular hemorrhage in a patient with COVID-19
Mastropasqua R.
2020
Abstract
Purpose: We report a case of a patient with a known hereditary spherocytosis who developed a bilateral macular hemorrhage in concurrence with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related respiratory syndrome. Observations: Blood tests showed severe hemolytic anemia. Interestingly, the peripheral blood smear demonstrated a mixed pathogenesis of the hemolytic process (cold-agglutinin-mediated and non-immune-mediated due to spherocytosis). Conclusions and Importance: We argue that SARS-CoV-2 could have triggered the hemolytic process, which led to retinal hemorrhages due to endothelial anoxia from the low oxygen carrying capacity.File | Dimensione | Formato | |
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