Aim: The aim of this study was to determine the efficacy of a new topic non-hormonal treatment for postmenopausal women complaining of symptoms of vaginal atrophy. Methods: Patients included in the study were prescribed Sinecol gel (AM PHARMA Srl, Vimercate, Monza and Brianza, Italy) application once a day for 20 consecutive days. Sinecol gel is a topic compound for vaginal atrophy containing hyaluronic acid, that is known to improve vaginal elasticity, lactoperoxidase, Xantham gum and glucose oxidase, which have protective and antibacterial action. We evaluated each patient before and after treatment, both subjectively with the "Visual Analogical Scale" (VAS) and objectively with the "Vaginal Health Index" (VHI). Results: We observed a significant clinical improvement of the subjective and objective assessment of symptoms severity with ap value <0.001 at the end of the treatment compared to baseline. Conclusion: Sinecol gel appears to be an effective and valid non-hormonal alternative to the estrogen therapy for vaginal atrophy.

An alternative approach for the treatment of vaginal atrophy / Quaranta, L.; Ottolina, J.; Parma, M.; Chionna, R.; Sileo, F.; Dindelli, M.; Origoni, M.; Candiani, M.; Salvatore, S.. - In: MINERVA GINECOLOGICA. - ISSN 0026-4784. - 66:4(2014), pp. 377-381.

An alternative approach for the treatment of vaginal atrophy

Sileo F.;
2014

Abstract

Aim: The aim of this study was to determine the efficacy of a new topic non-hormonal treatment for postmenopausal women complaining of symptoms of vaginal atrophy. Methods: Patients included in the study were prescribed Sinecol gel (AM PHARMA Srl, Vimercate, Monza and Brianza, Italy) application once a day for 20 consecutive days. Sinecol gel is a topic compound for vaginal atrophy containing hyaluronic acid, that is known to improve vaginal elasticity, lactoperoxidase, Xantham gum and glucose oxidase, which have protective and antibacterial action. We evaluated each patient before and after treatment, both subjectively with the "Visual Analogical Scale" (VAS) and objectively with the "Vaginal Health Index" (VHI). Results: We observed a significant clinical improvement of the subjective and objective assessment of symptoms severity with ap value <0.001 at the end of the treatment compared to baseline. Conclusion: Sinecol gel appears to be an effective and valid non-hormonal alternative to the estrogen therapy for vaginal atrophy.
2014
66
4
377
381
An alternative approach for the treatment of vaginal atrophy / Quaranta, L.; Ottolina, J.; Parma, M.; Chionna, R.; Sileo, F.; Dindelli, M.; Origoni, M.; Candiani, M.; Salvatore, S.. - In: MINERVA GINECOLOGICA. - ISSN 0026-4784. - 66:4(2014), pp. 377-381.
Quaranta, L.; Ottolina, J.; Parma, M.; Chionna, R.; Sileo, F.; Dindelli, M.; Origoni, M.; Candiani, M.; Salvatore, S.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1249252
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