Ever changing problems in agricultural weed control require periodic introduction of new herbicides. Imidazo[4,5-c]pyrazoles, which were considered of interest as potential herbicides, were synthesized and examined for the pre-emergence, post-emergence, and post-transplant control of weeds in rice against broadleaf and grass weed species. The data obtained suggest that some imidazo[4,5-c]pyrazoles have potential herbicidal activity against a wide range of weeds, with 5-methyl, 5-thiomethyl, and 5-unsubstituted derivatives being the most effective. No herbicidal activity was observed in the 5-methylsulfonylimidazo[4,5-c]pyrazole and imidazo[4,5-c]pyrazolone series.

Synthesis of a novel series of imidazo[4,5-c]pyrazole derivatives and their evaluation as herbicidal agents / Vicentini, C. B.; Manfrini, M.; Mazzanti, M.; Scatturin, A.; Romagnoli, C.; Mares, D.. - In: ARCHIV DER PHARMAZIE. - ISSN 0365-6233. - 332:10(1999), pp. 337-342. [10.1002/(SICI)1521-4184(199910)332:10<337::AID-ARDP337>3.0.CO;2-P]

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