Several physical and biological mechanisms can drive progression between the different phases of lung injury due to SARS-CoV-2 infection, thus modifying the mechanical properties and behavior of COVID-19 over time. In this research letter we have presented the findings of a registered clinical trial aimed at describing and comparing the inspiratory effort (primary outcome) and the breathing pattern of spontaneously breathing patients with ARF in COVID-19 and historically matched non-COVID-19 patients, either candidate to NIV. Moreover, we reported the response to a 2 hours NIV trial in the two groups. Spontaneously breathing COVID-19 at their early onset of acute respiratory failure with indication for NIV showed different mechanical characteristics and breathing pattern when compared with non-COVID-19.

Inspiratory effort and lung mechanics in spontaneously breathing patients with acute respiratory failure due to COVID-19. A matched control study / Tonelli, R; Busani, S; Tabbì, L; Fantini, R; Castaniere, I; Biagioni, E; Mussini, C; Girardis, M; Clini, E; Marchioni, A.. - In: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. - ISSN 1535-4970. - 204:6(2021), pp. 725-728. [10.1164/rccm.202104-1029LE]

Inspiratory effort and lung mechanics in spontaneously breathing patients with acute respiratory failure due to COVID-19. A matched control study.

Tonelli, R;Busani, S;Castaniere, I;Mussini, C;Girardis, M;Clini, E;Marchioni, A.
2021

Abstract

Several physical and biological mechanisms can drive progression between the different phases of lung injury due to SARS-CoV-2 infection, thus modifying the mechanical properties and behavior of COVID-19 over time. In this research letter we have presented the findings of a registered clinical trial aimed at describing and comparing the inspiratory effort (primary outcome) and the breathing pattern of spontaneously breathing patients with ARF in COVID-19 and historically matched non-COVID-19 patients, either candidate to NIV. Moreover, we reported the response to a 2 hours NIV trial in the two groups. Spontaneously breathing COVID-19 at their early onset of acute respiratory failure with indication for NIV showed different mechanical characteristics and breathing pattern when compared with non-COVID-19.
3-lug-2021
204
6
725
728
Inspiratory effort and lung mechanics in spontaneously breathing patients with acute respiratory failure due to COVID-19. A matched control study / Tonelli, R; Busani, S; Tabbì, L; Fantini, R; Castaniere, I; Biagioni, E; Mussini, C; Girardis, M; Clini, E; Marchioni, A.. - In: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. - ISSN 1535-4970. - 204:6(2021), pp. 725-728. [10.1164/rccm.202104-1029LE]
Tonelli, R; Busani, S; Tabbì, L; Fantini, R; Castaniere, I; Biagioni, E; Mussini, C; Girardis, M; Clini, E; Marchioni, A.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1247899
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