On March 11, 2020, the World Health Organization declared coronavirus disease 2019 (COVID-19) a pandemic; from that date, the vaccine race has begun, and many technology platforms to develop a specific and effective COVID-19 vaccine have been launched in several clinical trials (protein subunit, RNA-based, DNA-based, replicating viral vector, nonreplicating viral vector, inactivated virus, live attenuated virus, and virus-like particle). Among the next-generation strategies, nucleoside-modified messenger RNA vaccines appear the most attractive, not only to counteract emerging pathogens but also for the possible applications in regenerative medicine and cancer therapy. However, exactly as all innovative drugs, they deserve careful pharmacovigilance in the short and long term.

Nucleoside-modified messenger RNA COVID-19 vaccine platform / Roncati, L.; Corsi, L.. - In: JOURNAL OF MEDICAL VIROLOGY. - ISSN 0146-6615. - 93:7(2021), pp. 4054-4057. [10.1002/jmv.26924]

Nucleoside-modified messenger RNA COVID-19 vaccine platform

Roncati L.;Corsi L.
2021

Abstract

On March 11, 2020, the World Health Organization declared coronavirus disease 2019 (COVID-19) a pandemic; from that date, the vaccine race has begun, and many technology platforms to develop a specific and effective COVID-19 vaccine have been launched in several clinical trials (protein subunit, RNA-based, DNA-based, replicating viral vector, nonreplicating viral vector, inactivated virus, live attenuated virus, and virus-like particle). Among the next-generation strategies, nucleoside-modified messenger RNA vaccines appear the most attractive, not only to counteract emerging pathogens but also for the possible applications in regenerative medicine and cancer therapy. However, exactly as all innovative drugs, they deserve careful pharmacovigilance in the short and long term.
2021
93
7
4054
4057
Nucleoside-modified messenger RNA COVID-19 vaccine platform / Roncati, L.; Corsi, L.. - In: JOURNAL OF MEDICAL VIROLOGY. - ISSN 0146-6615. - 93:7(2021), pp. 4054-4057. [10.1002/jmv.26924]
Roncati, L.; Corsi, L.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1241975
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