The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the presence of lamivudine and adefovir resistance mutations in clinical samples, has a high degree of concordance with sequencing, and can detect mutants earlier.
Sensitive line probe assay that simultaneously detects mutations conveying resistance to lamivudine and adefovir / Hussain, M.; Fung, S.; Libbrecht, E.; Sablon, E.; Cursaro, C.; Andreone, Pietro; Lok, A. S.. - In: JOURNAL OF CLINICAL MICROBIOLOGY. - ISSN 0095-1137. - 44:3(2006), pp. 1094-1097. [10.1128/JCM.44.3.1094-1097.2006]
Sensitive line probe assay that simultaneously detects mutations conveying resistance to lamivudine and adefovir
ANDREONE, PIETRO;
2006
Abstract
The INNO-LiPA HBV DR v2 assay is designed to detect hepatitis B virus mutations conveying resistance to lamivudine and adefovir. Our study confirms that this assay can simultaneously detect the presence of lamivudine and adefovir resistance mutations in clinical samples, has a high degree of concordance with sequencing, and can detect mutants earlier.
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