The effects of the exposure of mitogen-stimulated human lymphocytes from young and aged subjects to low-frequency pulsed electromagnetic fields (PEMFs) were studied, by measuring cell proliferation, production and utilization of interleukin-2 (IL-2) and the expression of IL-2 receptors. Moreover, data are presented about DNA repair, cell survival and genotoxic effects in cultures exposed to PEMFs. PEMFs increased DNA synthesis, and the effect was more pronunced in the cells from very old subjects. Moreover a higher percentage of IL-2 receptor-positive cells and T-activated lymphocytes was found in the exposed cultures. No effects were found as far as DNA repair and genotoxic effects are concerned.
Effects of extremely low frequency (ELF) pulsed electromagnetic fields (PEMFs) on immunocompetent cells / Bersani, Ferdinando; Cossarizza, Andrea; Franceschi, Claudio. - In: ALTA FREQUENZA. - ISSN 0002-6557. - 58:4(1989), pp. 375-380.
Effects of extremely low frequency (ELF) pulsed electromagnetic fields (PEMFs) on immunocompetent cells
Cossarizza Andrea;Franceschi Claudio
1989
Abstract
The effects of the exposure of mitogen-stimulated human lymphocytes from young and aged subjects to low-frequency pulsed electromagnetic fields (PEMFs) were studied, by measuring cell proliferation, production and utilization of interleukin-2 (IL-2) and the expression of IL-2 receptors. Moreover, data are presented about DNA repair, cell survival and genotoxic effects in cultures exposed to PEMFs. PEMFs increased DNA synthesis, and the effect was more pronunced in the cells from very old subjects. Moreover a higher percentage of IL-2 receptor-positive cells and T-activated lymphocytes was found in the exposed cultures. No effects were found as far as DNA repair and genotoxic effects are concerned.
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