Background: No specific features of nevus-associated melanoma (NAM) are currently defined. Objective: To identify clinical/dermoscopic features of NAM. Methods: Retrospective evaluation of histopathologically diagnosed NAM. Results: Eighty of 165 NAMs had a clinically recognizable nevus component, often raised or nodular, most frequently characterized by different morphologic clones and/or colors. In 111 of 165 NAMs, dermoscopy showed a nevus component, prevalently characterized by regular dots/clods and structureless brown areas. Clinically, the melanoma component was eccentric/peripheral in 45 of 80 cases and central in 35 of 80; dermoscopically, the figures were 59 of 111 and 52 of 111, respectively. Melanomas associated with congenital nevi (C-NAMs) occur at a younger age and have a thicker Breslow depth than melanomas associated with acquired nevi (NC-NAMs). Dermoscopically, regular dots/globules characterize C-NAMs, and hypopigmented structureless areas characterize NC-NAMs. Limitations: Retrospective analysis. Conclusion: C-NAMs are more often central to a congenital nevus, with a clod/globular or structureless brown pattern, typical of young patients. NC-NAMs are frequently hypopigmented nodules/plaques, eccentric/peripheral, with hypopigmented structureless areas, typical of older patients.
Clinical and dermoscopic characteristics of congenital and noncongenital nevus-associated melanomas / Zalaudek, I.; Conforti, C.; Guarneri, F.; Vezzoni, R.; Deinlein, T.; Hofmann-Wellenhof, R.; Longo, C.; Moscarella, E.; Kittler, H.; Argenziano, G.; Giuffrida, R.. - In: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. - ISSN 0190-9622. - 83:4(2020), pp. 1080-1087.
Data di pubblicazione: | 2020 |
Titolo: | Clinical and dermoscopic characteristics of congenital and noncongenital nevus-associated melanomas |
Autore/i: | Zalaudek, I.; Conforti, C.; Guarneri, F.; Vezzoni, R.; Deinlein, T.; Hofmann-Wellenhof, R.; Longo, C.; Moscarella, E.; Kittler, H.; Argenziano, G.; Giuffrida, R. |
Autore/i UNIMORE: | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/j.jaad.2020.04.120 |
Rivista: | |
Volume: | 83 |
Fascicolo: | 4 |
Pagina iniziale: | 1080 |
Pagina finale: | 1087 |
Codice identificativo ISI: | WOS:000569306800015 |
Codice identificativo Scopus: | 2-s2.0-85089400154 |
Codice identificativo Pubmed: | 32360715 |
Citazione: | Clinical and dermoscopic characteristics of congenital and noncongenital nevus-associated melanomas / Zalaudek, I.; Conforti, C.; Guarneri, F.; Vezzoni, R.; Deinlein, T.; Hofmann-Wellenhof, R.; Longo, C.; Moscarella, E.; Kittler, H.; Argenziano, G.; Giuffrida, R.. - In: JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. - ISSN 0190-9622. - 83:4(2020), pp. 1080-1087. |
Tipologia | Articolo su rivista |
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