OBJECTIVES. Omega-3 fatty acids have proven a potent anti-inflammatory action in the human body. This article considers the actions that reduce the inflammatory response created by periodontal disease, actions which would induce a modulation of periodontal inflammatory cascade. MATERIALS AND METHODS. A review of the literature was performed by inserting the following key words both in English and Italian: periodontal disease, periodontitis, omega-3, anti-aging medicine and polyunsaturated fatty acids. Only scientific articles and textbooks published between 1965 and 2015 were included. RESULTS. Omega-3 exert a significant action on inflammatory mediators, thereby regulating inflammation related to oxidative stress and promoting repair of periodontal tissues. CONCLUSIONS. Periodontal therapy may be supported by the use of omega-3 in modulating the host's immuno inflammatory-response, reducing the destructive aspects of the response itself.
Relationship between omega-3 and periodontitis: Literature review / Ongaro, F.; Checchi, V.; Papale, C.; Rossi, R.; Tissino, B.; Checchi, L.. - In: DENTAL CADMOS. - ISSN 0011-8524. - 85:3(2017), pp. 126-134. [10.19256/d.cadmos.03.2017.04]
Relationship between omega-3 and periodontitis: Literature review
Checchi V.;
2017
Abstract
OBJECTIVES. Omega-3 fatty acids have proven a potent anti-inflammatory action in the human body. This article considers the actions that reduce the inflammatory response created by periodontal disease, actions which would induce a modulation of periodontal inflammatory cascade. MATERIALS AND METHODS. A review of the literature was performed by inserting the following key words both in English and Italian: periodontal disease, periodontitis, omega-3, anti-aging medicine and polyunsaturated fatty acids. Only scientific articles and textbooks published between 1965 and 2015 were included. RESULTS. Omega-3 exert a significant action on inflammatory mediators, thereby regulating inflammation related to oxidative stress and promoting repair of periodontal tissues. CONCLUSIONS. Periodontal therapy may be supported by the use of omega-3 in modulating the host's immuno inflammatory-response, reducing the destructive aspects of the response itself.
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