In 'Biopsy Outperforms Reflectance Confocal Microscopy in Diagnosing and Subtyping Basal Cell Carcinoma: Results and Experiences from a Randomized Controlled Multicentre Trial', the authors found that reflectance confocal microscopy (RCM) identifies basal cell carcinoma (BCC) with 99% sensitivity and, impressively, distinguishes superficial BCCs from more aggressive BCCs with 88.9% sensitivity compared to punch biopsy (PB) at 91%,1 a difference without statistical significance.
Lost in Translation: True Clinical Impact of RCM Overlooked in "Biopsy outperforms Reflectance Confocal Microscopy in Diagnosing and Subtyping Basal Cell Carcinoma: Results and Experiences from a Randomized Controlled Multicentre Trial" / Gill, M; Pellacani, G; Grant-Kels, J M; Ardigò, M; Chen, C-S J; Gonzalez, S; Guitera, P; Longo, C; Malvehy, J; Markowitz, O; Puig, S; Rabinovitz, H; Rao, B K; Scope, A; Ulrich, M. - In: BRITISH JOURNAL OF DERMATOLOGY. - ISSN 0007-0963. - 184:4(2021), pp. 775-776. [10.1111/bjd.19602]
Lost in Translation: True Clinical Impact of RCM Overlooked in "Biopsy outperforms Reflectance Confocal Microscopy in Diagnosing and Subtyping Basal Cell Carcinoma: Results and Experiences from a Randomized Controlled Multicentre Trial"
Pellacani, G;Longo, C;
2021
Abstract
In 'Biopsy Outperforms Reflectance Confocal Microscopy in Diagnosing and Subtyping Basal Cell Carcinoma: Results and Experiences from a Randomized Controlled Multicentre Trial', the authors found that reflectance confocal microscopy (RCM) identifies basal cell carcinoma (BCC) with 99% sensitivity and, impressively, distinguishes superficial BCCs from more aggressive BCCs with 88.9% sensitivity compared to punch biopsy (PB) at 91%,1 a difference without statistical significance.
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