Transformed mycosis fungoides (tMF) is a rare variant of MF with an aggressive course. In this study, we describe the patient characteristics, treatments, and outcomes of 17 patients with tMF in COMPLETE: a multicenter, prospective US cohort study of peripheral T-cell lymphoma. Responses were observed with single agents, but survival remains poor. Novel treatment approaches are urgently needed to improve outcomes.
Outcomes of Patients with Transformed Mycosis Fungoides: Analysis from a Prospective Multicenter US Cohort Study / Lansigan, F.; Horwitz, S. M.; Pinter-Brown, L. C.; Carson, K. R.; Shustov, A. R.; Rosen, S. T.; Pro, B.; Hsi, E. D.; Federico, M.; Gisselbrecht, C.; Schwartz, M.; Bellm, L. A.; Acosta, M.; Foss, F. M.. - In: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. - ISSN 2152-2650. - 20:11(2020), pp. 744-748. [10.1016/j.clml.2020.05.001]
Outcomes of Patients with Transformed Mycosis Fungoides: Analysis from a Prospective Multicenter US Cohort Study
Federico M.;
2020
Abstract
Transformed mycosis fungoides (tMF) is a rare variant of MF with an aggressive course. In this study, we describe the patient characteristics, treatments, and outcomes of 17 patients with tMF in COMPLETE: a multicenter, prospective US cohort study of peripheral T-cell lymphoma. Responses were observed with single agents, but survival remains poor. Novel treatment approaches are urgently needed to improve outcomes.
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