Transformed mycosis fungoides (tMF) is a rare variant of MF with an aggressive course. In this study, we describe the patient characteristics, treatments, and outcomes of 17 patients with tMF in COMPLETE: a multicenter, prospective US cohort study of peripheral T-cell lymphoma. Responses were observed with single agents, but survival remains poor. Novel treatment approaches are urgently needed to improve outcomes.
Outcomes of Patients with Transformed Mycosis Fungoides: Analysis from a Prospective Multicenter US Cohort Study / Lansigan, F., Horwitz, S.M., Pinter-Brown, L.C., Carson, K.R., Shustov, A.R., Rosen, S.T., Pro, B., Hsi, E.D., Federico, M., Gisselbrecht, C., Schwartz, M., Bellm, L.A., Acosta, M., Foss, F.M.. - In: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA. - ISSN 2152-2650. - 20:11(2020), pp. 744-748. [10.1016/j.clml.2020.05.001]
Outcomes of Patients with Transformed Mycosis Fungoides: Analysis from a Prospective Multicenter US Cohort Study
Federico M.;
2020
Abstract
Transformed mycosis fungoides (tMF) is a rare variant of MF with an aggressive course. In this study, we describe the patient characteristics, treatments, and outcomes of 17 patients with tMF in COMPLETE: a multicenter, prospective US cohort study of peripheral T-cell lymphoma. Responses were observed with single agents, but survival remains poor. Novel treatment approaches are urgently needed to improve outcomes.
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