Visualization of phosphorylated α-synuclein at serine 129 (p-syn) in skin nerves is a promising test for the in vivo diagnosis of synucleinopathies. Here we aimed to establish the intra- and inter-laboratory reproducibility of quantification of intraneural p-syn immunoreactivity in two laboratories with a major expertise (Würzburg and Bologna).
Abnormal α-synuclein deposits in skin nerves: intra- and inter-laboratory reproducibility / Donadio, V., Doppler, K., Incensi, A., Kuzkina, A., Janzen, A., Mayer, G., Volkmann, J., Rizzo, G., Antelmi, E., Plazzi, G., Sommer, C., Liguori, R., Oertel, W.H.. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - 26:10(2019), pp. 1245-1251. [10.1111/ene.13939]
Abnormal α-synuclein deposits in skin nerves: intra- and inter-laboratory reproducibility
Plazzi, G;
2019
Abstract
Visualization of phosphorylated α-synuclein at serine 129 (p-syn) in skin nerves is a promising test for the in vivo diagnosis of synucleinopathies. Here we aimed to establish the intra- and inter-laboratory reproducibility of quantification of intraneural p-syn immunoreactivity in two laboratories with a major expertise (Würzburg and Bologna).
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