Visualization of phosphorylated α-synuclein at serine 129 (p-syn) in skin nerves is a promising test for the in vivo diagnosis of synucleinopathies. Here we aimed to establish the intra- and inter-laboratory reproducibility of quantification of intraneural p-syn immunoreactivity in two laboratories with a major expertise (Würzburg and Bologna).
Abnormal α-synuclein deposits in skin nerves: intra- and inter-laboratory reproducibility / Donadio, V; Doppler, K; Incensi, A; Kuzkina, A; Janzen, A; Mayer, G; Volkmann, J; Rizzo, G; Antelmi, E; Plazzi, G; Sommer, C; Liguori, R; Oertel, W H. - In: EUROPEAN JOURNAL OF NEUROLOGY. - ISSN 1351-5101. - 26:10(2019), pp. 1245-1251. [10.1111/ene.13939]
Abnormal α-synuclein deposits in skin nerves: intra- and inter-laboratory reproducibility
Plazzi, G;
2019
Abstract
Visualization of phosphorylated α-synuclein at serine 129 (p-syn) in skin nerves is a promising test for the in vivo diagnosis of synucleinopathies. Here we aimed to establish the intra- and inter-laboratory reproducibility of quantification of intraneural p-syn immunoreactivity in two laboratories with a major expertise (Würzburg and Bologna).
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