To validate polysomnographic markers (sleep latency and sleep-onset REM periods [SOREMPs] at the Multiple Sleep Latency Test [MSLT] and nocturnal polysomnography [PSG]) for pediatric narcolepsy type 1 (NT1) against CSF hypocretin-1 (hcrt-1) deficiency and presence of cataplexy, as no criteria are currently validated in children.
Validation of Multiple Sleep Latency Test for the diagnosis of pediatric narcolepsy type 1 / Pizza, Fabio; Barateau, Lucie; Jaussent, Isabelle; Vandi, Stefano; Antelmi, Elena; Mignot, Emmanuel; Dauvilliers, Yves; Plazzi, Giuseppe. - In: NEUROLOGY. - ISSN 0028-3878. - 93:11(2019), pp. e1034-e1044. [10.1212/WNL.0000000000008094]
Validation of Multiple Sleep Latency Test for the diagnosis of pediatric narcolepsy type 1
Plazzi, Giuseppe
2019
Abstract
To validate polysomnographic markers (sleep latency and sleep-onset REM periods [SOREMPs] at the Multiple Sleep Latency Test [MSLT] and nocturnal polysomnography [PSG]) for pediatric narcolepsy type 1 (NT1) against CSF hypocretin-1 (hcrt-1) deficiency and presence of cataplexy, as no criteria are currently validated in children.
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