Study Objectives: The study was aimed at estimating the effect of alcohol consumption, time of day, and their interaction on traffic crashes in a real regional context. Methods: Blood alcohol concentration (BAC) data were collected from drivers involved in traffic accidents during one year in an Italian region and in a control group of drivers over the same road network. Mean circadian sleep propensity was estimated from a previous study as function of time of day. Accident risk was analyzed by logistic regression as function of BAC and circadian sleep propensity. Results: BAC values greater than zero were found in 72.0% of the drivers involved in crashes and in 40.4% of the controls. Among the former 23.6% of the drivers exceeded the BAC legal threshold of 0.05 g/dL, while illegal values were found in 10.4% of the controls. The relative risk showed a significant increase with both BAC and circadian sleep propensity (as estimated from time of day) and their interaction was significant. Conclusions: Due to the significant interaction, even low BAC levels strongly increased accident risk when associated with high sleep propensity.
Circadian sleep propensity and alcohol interaction at the wheel / Garbarino, Sergio; Nobili, Lino; Philip, Pierre; Plazzi, Giuseppe; Campus, Claudio; Morrone, Elisa; De Carli, Fabrizio. - In: JOURNAL OF CLINICAL SLEEP MEDICINE. - ISSN 1550-9389. - 12:7(2016), pp. 1011-1017.
Data di pubblicazione: | 2016 |
Titolo: | Circadian sleep propensity and alcohol interaction at the wheel |
Autore/i: | Garbarino, Sergio; Nobili, Lino; Philip, Pierre; Plazzi, Giuseppe; Campus, Claudio; Morrone, Elisa; De Carli, Fabrizio |
Autore/i UNIMORE: | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.5664/jcsm.5938 |
Rivista: | |
Volume: | 12 |
Fascicolo: | 7 |
Pagina iniziale: | 1011 |
Pagina finale: | 1017 |
Codice identificativo ISI: | WOS:000389988200012 |
Codice identificativo Scopus: | 2-s2.0-84980041571 |
Codice identificativo Pubmed: | 27166301 |
Citazione: | Circadian sleep propensity and alcohol interaction at the wheel / Garbarino, Sergio; Nobili, Lino; Philip, Pierre; Plazzi, Giuseppe; Campus, Claudio; Morrone, Elisa; De Carli, Fabrizio. - In: JOURNAL OF CLINICAL SLEEP MEDICINE. - ISSN 1550-9389. - 12:7(2016), pp. 1011-1017. |
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