Narcolepsy with cataplexy is a severely disabling disorder very often arising in childhood. Data on neuropsychological impairment in children are scant. We administered standardized neuropsychological tests to 13 children with narcolepsy with cataplexy. Overall, our patients displayed multiple patterns of cognitive and behavioral dysfunction, and often academic failure (7 cases out of 13). All children had a normal full intelligence quotient (IQ), but 3 patients presented a significantly higher and 2 a significantly lower Verbal IQ compared to Performance IQ, respectively. Mean sleep latency was significantly correlated (P < .05) to alertness functions. Eight patients displayed behavioral problems: emotional symptoms and conduct problems prevailed. Childhood narcolepsy with cataplexy represents a risk factor for subtle and heterogeneous cognitive impairments potentially resulting in academic failure, despite the normal IQ. These children also have a certain psychopathological risk. All this seems to be at least partially detached from the direct effects of daytime sleepiness.

Neuropsychological findings in childhood narcolepsy / Posar, A.; Pizza, F.; Parmeggiani, A.; Plazzi, G.. - In: JOURNAL OF CHILD NEUROLOGY. - ISSN 0883-0738. - 29:10(2014), pp. 1370-1376. [10.1177/0883073813508315]

Neuropsychological findings in childhood narcolepsy

Posar A.;Parmeggiani A.;Plazzi G.
2014

Abstract

Narcolepsy with cataplexy is a severely disabling disorder very often arising in childhood. Data on neuropsychological impairment in children are scant. We administered standardized neuropsychological tests to 13 children with narcolepsy with cataplexy. Overall, our patients displayed multiple patterns of cognitive and behavioral dysfunction, and often academic failure (7 cases out of 13). All children had a normal full intelligence quotient (IQ), but 3 patients presented a significantly higher and 2 a significantly lower Verbal IQ compared to Performance IQ, respectively. Mean sleep latency was significantly correlated (P < .05) to alertness functions. Eight patients displayed behavioral problems: emotional symptoms and conduct problems prevailed. Childhood narcolepsy with cataplexy represents a risk factor for subtle and heterogeneous cognitive impairments potentially resulting in academic failure, despite the normal IQ. These children also have a certain psychopathological risk. All this seems to be at least partially detached from the direct effects of daytime sleepiness.
2014
29
10
1370
1376
Neuropsychological findings in childhood narcolepsy / Posar, A.; Pizza, F.; Parmeggiani, A.; Plazzi, G.. - In: JOURNAL OF CHILD NEUROLOGY. - ISSN 0883-0738. - 29:10(2014), pp. 1370-1376. [10.1177/0883073813508315]
Posar, A.; Pizza, F.; Parmeggiani, A.; Plazzi, G.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1205823
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