Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially fatal complication of pulmonary embolism (PE). Organized thrombus in the pulmonary artery causes a chronic obstruction, leading to a vascular system remodeling, an increase of pulmonary vascular resistance and a chronic pulmonary hypertension. Epidemiology is mostly unknown due to the difficult diagnostic process that often leads to a late diagnosis: findings of persistent pulmonary hypertension (PH), despite correct treatment of PE, lead to the diagnostic suspect. The first choice treatment is pulmonary endarterectomy (PEA) associated with lifelong anticoagulant therapy with vitamin K antagonist. We present the case of a 53-year-old male affected by dyspnea for months, admitted to a sub-intensive care unit for intermediate low-risk PE; echocardiography showed signs of PH persisting after anticoagulant therapy; after 2 months of specific treatment the diagnosis of CTEPH was confirmed and the patient was successfully treated with PEA.

A case of chronic thromboembolic pulmonary hypertension / Brugioni, Lucio; Mazzali, Eleonora; Catena, Chiara; Mori, Francesca; Benatti, Francesco; De Niedehausern, Francesca; Vivoli, Daniela; Borsatti, Andrea; Aramini, Beatrice; Romagnoli, Elisa. - In: ITALIAN JOURNAL OF MEDICINE. - ISSN 1877-9352. - 14:2(2020), pp. 102-105. [10.4081/itjm.2020.1250]

A case of chronic thromboembolic pulmonary hypertension.

Eleonora Mazzali
Writing – Original Draft Preparation
;
Chiara Catena
Data Curation
;
Francesca Mori
Visualization
;
Francesco Benatti
Conceptualization
;
Beatrice Aramini
Visualization
;
Elisa Romagnoli
Writing – Review & Editing
2020

Abstract

Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially fatal complication of pulmonary embolism (PE). Organized thrombus in the pulmonary artery causes a chronic obstruction, leading to a vascular system remodeling, an increase of pulmonary vascular resistance and a chronic pulmonary hypertension. Epidemiology is mostly unknown due to the difficult diagnostic process that often leads to a late diagnosis: findings of persistent pulmonary hypertension (PH), despite correct treatment of PE, lead to the diagnostic suspect. The first choice treatment is pulmonary endarterectomy (PEA) associated with lifelong anticoagulant therapy with vitamin K antagonist. We present the case of a 53-year-old male affected by dyspnea for months, admitted to a sub-intensive care unit for intermediate low-risk PE; echocardiography showed signs of PH persisting after anticoagulant therapy; after 2 months of specific treatment the diagnosis of CTEPH was confirmed and the patient was successfully treated with PEA.
2020
14
2
102
105
A case of chronic thromboembolic pulmonary hypertension / Brugioni, Lucio; Mazzali, Eleonora; Catena, Chiara; Mori, Francesca; Benatti, Francesco; De Niedehausern, Francesca; Vivoli, Daniela; Borsatti, Andrea; Aramini, Beatrice; Romagnoli, Elisa. - In: ITALIAN JOURNAL OF MEDICINE. - ISSN 1877-9352. - 14:2(2020), pp. 102-105. [10.4081/itjm.2020.1250]
Brugioni, Lucio; Mazzali, Eleonora; Catena, Chiara; Mori, Francesca; Benatti, Francesco; De Niedehausern, Francesca; Vivoli, Daniela; Borsatti, Andrea...espandi
File in questo prodotto:
File Dimensione Formato  
Brugioni et al. 2020.pdf

Open access

Tipologia: Versione pubblicata dall'editore
Dimensione 1 MB
Formato Adobe PDF
1 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1204509
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact