Objective: To study the prevalence of congenital syphilis and its risk factors in Italy. Study design: Prospective study from 1 July 2006 to 30 June 2007. Data on mother-child pairs were collected for every syphilis seropositive mother. Results: Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100 000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. Discussion: Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. Conclusion: Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
Congenital syphilis in Italy: A multicentre study / Tridapalli, E., Capretti, M.G., Reggiani, M.L.B., Stronati, M., Faldella, G., Auriti, C., Balata, A., Barera, G., Bennato, E., Berardi, A., Bolognesi, S., Bonomi, A., Boulos, F., Brambilla, C., Branchi, M., Cabiati, G., Caddia, V., Calzetti, G., Campanile, A., Cataldo, P., et al.. - In: ARCHIVES OF DISEASE IN CHILDHOOD. FETAL AND NEONATAL EDITION. - ISSN 1359-2998. - 97:3(2012), pp. F211-F213. [10.1136/adc.2010.183863]
Congenital syphilis in Italy: A multicentre study
Berardi A.;
2012
Abstract
Objective: To study the prevalence of congenital syphilis and its risk factors in Italy. Study design: Prospective study from 1 July 2006 to 30 June 2007. Data on mother-child pairs were collected for every syphilis seropositive mother. Results: Maternal syphilis seroprevalence at delivery was 0.17%. 207 infants were born to 203 syphilis seropositive mothers. In 25 newborns it was possible to diagnose congenital syphilis (20/100 000 live births). Maternal risk factors included age <20 years, no antenatal care and no adequate treatment. The infected babies were more often preterm or weighed <2000 g at birth. Discussion: Many syphilis seropositive mothers were foreign born but the risk of an infected newborn was not higher in foreign-born than in Italian seropositive women. The significant factors were lack of antenatal screening and inadequate maternal treatment. Conclusion: Syphilis is a re-emerging infection in Italy. Prevention strategies should include antenatal serological tests for all pregnant women and treatment for infected mothers.
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