Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did not require mechanical ventilation. During the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, transplant clinicians should be readily informed about new cases of COVID-19 pneumonia in solid organ transplant recipients, with focus on therapeutic strategies employed and their outcome.
COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine / Fontana, Francesco; Alfano, Gaetano; Mori, Giacomo; Amurri, Alessio; Tei, Lorenzo; Ballestri, Marco; Leonelli, Marco; Facchini, Francesca; Damiano, Francesca; Magistroni, Riccardo; Cappelli, Gianni. - In: AMERICAN JOURNAL OF TRANSPLANTATION. - ISSN 1600-6135. - 20:7(2020), pp. 1902-1906. [10.1111/ajt.15935]
COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine
Fontana, Francesco;Alfano, Gaetano;Mori, Giacomo;Amurri, Alessio;Tei, Lorenzo;Damiano, Francesca;Magistroni, Riccardo;Cappelli, Gianni
2020-01-01
Abstract
Coronavirus disease 2019 (COVID-19) pneumonia has been poorly reported in solid organ transplanted patients; prognosis is uncertain and best management unclear. We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did not require mechanical ventilation. During the rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, transplant clinicians should be readily informed about new cases of COVID-19 pneumonia in solid organ transplant recipients, with focus on therapeutic strategies employed and their outcome.
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