Neuroendocrine tumors of the pancreas (NETP) represent only 1%-2% of all pancreatic neoplasms. They can be classified as functioning or non-functioning, respectively, according to the presence or absence of paraneoplastic syndrome. Case 1 concerned a 70-year-old woman with a cystic lesion of the pancreatic head and body. All tumor markers were negative. The patient underwent a distal pancreatectomy. The histology revealed a well-differentiated endocrine tumor with uncertain malignant potential. Case 2 was a 61-year-old man with chronic polyserositis. The serum tumor markers were negative, while he was strongly positive for intracystic tumor markers carcinoembryonic antigen, carbohydrate antigen (CA) 19-9, and CA 125. The patient underwent a cephalo-pancreatic duodenectomy. The preoperative differential diagnosis of cystic NETP is still a challenge due to the high rate of the nonfunctional variant. Although cystic NETPs are well differentiated, they are still tumors with a malignant potential, and therefore an early diagnosis and radical surgical resection could be associated with a better long-term survival.

Cystic pancreatic neuroendocrine neoplasms with uncertain malignant potential: Report of two cases / Ballarin, R; Masetti, M; Losi, L; Di Benedetto, F; Di Sandro, S; De Ruvo, N; Montalti, R; Romano, A; Guerrini, Gp; DE BLASIIS, Maria Grazia; Spaggiari, M; Gerunda, Ge.. - In: SURGERY TODAY. - ISSN 0941-1291. - ELETTRONICO. - 39:2(2009), pp. 162-167. [10.1007/s00595-008-3806-7]

Cystic pancreatic neuroendocrine neoplasms with uncertain malignant potential: Report of two cases

Ballarin R;Masetti M;Di Benedetto F;Di Sandro S;Romano A;Guerrini GP;De Blasiis MG;Spaggiari M;Gerunda GE.
2009

Abstract

Neuroendocrine tumors of the pancreas (NETP) represent only 1%-2% of all pancreatic neoplasms. They can be classified as functioning or non-functioning, respectively, according to the presence or absence of paraneoplastic syndrome. Case 1 concerned a 70-year-old woman with a cystic lesion of the pancreatic head and body. All tumor markers were negative. The patient underwent a distal pancreatectomy. The histology revealed a well-differentiated endocrine tumor with uncertain malignant potential. Case 2 was a 61-year-old man with chronic polyserositis. The serum tumor markers were negative, while he was strongly positive for intracystic tumor markers carcinoembryonic antigen, carbohydrate antigen (CA) 19-9, and CA 125. The patient underwent a cephalo-pancreatic duodenectomy. The preoperative differential diagnosis of cystic NETP is still a challenge due to the high rate of the nonfunctional variant. Although cystic NETPs are well differentiated, they are still tumors with a malignant potential, and therefore an early diagnosis and radical surgical resection could be associated with a better long-term survival.
2009
39
2
162
167
Cystic pancreatic neuroendocrine neoplasms with uncertain malignant potential: Report of two cases / Ballarin, R; Masetti, M; Losi, L; Di Benedetto, F; Di Sandro, S; De Ruvo, N; Montalti, R; Romano, A; Guerrini, Gp; DE BLASIIS, Maria Grazia; Spaggiari, M; Gerunda, Ge.. - In: SURGERY TODAY. - ISSN 0941-1291. - ELETTRONICO. - 39:2(2009), pp. 162-167. [10.1007/s00595-008-3806-7]
Ballarin, R; Masetti, M; Losi, L; Di Benedetto, F; Di Sandro, S; De Ruvo, N; Montalti, R; Romano, A; Guerrini, Gp; DE BLASIIS, Maria Grazia; Spaggiari, M; Gerunda, Ge.
File in questo prodotto:
File Dimensione Formato  
Cystic-pancreatic-neuroendocrine-neoplasms-with-uncertain-malignant-potential-Report-of-two-cases_2009_Surgery-Today.pdf

Solo gestori archivio

Tipologia: Versione pubblicata dall'editore
Dimensione 464.13 kB
Formato Adobe PDF
464.13 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1202106
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 7
social impact