The mechanisms underlying the therapeutic activity of interferon-β in multiple sclerosis are still not completely understood. In the present study, we evaluated the short and long-term effects of interferon-β treatment on different subsets of regulatory T cells in relapsing-remitting multiple sclerosis patients biologically responsive to treatment because of mixovirus resistance protein A inducibility.
Simultaneous quantification of natural and inducible regulatory T-cell subsets during interferon-β therapy of multiple sclerosis patients / Chiarini, Marco; Capra, Ruggero; Serana, Federico; Bertoli, Diego; Sottini, Alessandra; Giustini, Viviana; Scarpazza, Cristina; Rovaris, Marco; Torri Clerici, Valentina; Ferraro, Diana; Galgani, Simonetta; Solaro, Claudio; Conti, Marta Zaffira; Visconti, Andrea; Imberti, Luisa. - In: JOURNAL OF TRANSLATIONAL MEDICINE. - ISSN 1479-5876. - 18:1(2020), pp. 169-169. [10.1186/s12967-020-02329-5]
Simultaneous quantification of natural and inducible regulatory T-cell subsets during interferon-β therapy of multiple sclerosis patients
Ferraro, Diana;
2020
Abstract
The mechanisms underlying the therapeutic activity of interferon-β in multiple sclerosis are still not completely understood. In the present study, we evaluated the short and long-term effects of interferon-β treatment on different subsets of regulatory T cells in relapsing-remitting multiple sclerosis patients biologically responsive to treatment because of mixovirus resistance protein A inducibility.
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