Plasma reduced glutathione (GSH) seems to reflect liver GSH content, we have assessed plasma GSH in patients with chronic headaches. We found a significant lower plasma GSH concentration was found with respect to controls. We teste a administartion of GSH IV and found that.v. GSH free plasma cysteine was 12 fold higher than in basal condition and all the pattern of plasma thiol groups was modified. This work suggests a possible protective effect of GSH administration in Chronic Headache patients.
Plasma glutathione level in chronic headache drug abuser patients / T., Trenti; Ferrari, Anna; Pini, Luigi Alberto; G., Sancez; G., Nappi; E., Sternieri. - In: CEPHALALGIA. - ISSN 0333-1024. - STAMPA. - 11 (Suppl 11):(1991), pp. 186-187.
Plasma glutathione level in chronic headache drug abuser patients
FERRARI, Anna;PINI, Luigi Alberto;
1991
Abstract
Plasma reduced glutathione (GSH) seems to reflect liver GSH content, we have assessed plasma GSH in patients with chronic headaches. We found a significant lower plasma GSH concentration was found with respect to controls. We teste a administartion of GSH IV and found that.v. GSH free plasma cysteine was 12 fold higher than in basal condition and all the pattern of plasma thiol groups was modified. This work suggests a possible protective effect of GSH administration in Chronic Headache patients.
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