Enzymatic systems able to reduce either dehydroascorbate or ascorbyl radical back to ascorbate by "recycling" vitamin C may contribute to lowering the nutritional requirement of it and to increase tissue antioxidant capacity. The activities of two enzymatic activities, GSH-dehydroascorbate reductase (two-electron reduction pathway) and NADH-semidehydroascorbate reductase (one-electron reduction pathway) in pig tissues, have been investigated. The activity of glutathione-dependent reduction of dehydroascorbate, although measurable, appeared negligible taking into consideration the low physiological substrate concentration. On the other hand, the one-electron reduction of ascorbyl radical resulted fast enough to slow down the consumption of the antioxidant vitamin.

ENZYMATIC RECYCLING OF OXIDIZED ASCORBATE IN PIG-HEART - ONE-ELECTRON VS 2-ELECTRON PATHWAY / Coassin, M; Tomasi, Aldo; Vannini, V; Ursini, F.. - In: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. - ISSN 0003-9861. - STAMPA. - 290:(1991), pp. 458-462.

ENZYMATIC RECYCLING OF OXIDIZED ASCORBATE IN PIG-HEART - ONE-ELECTRON VS 2-ELECTRON PATHWAY

TOMASI, Aldo;
1991

Abstract

Enzymatic systems able to reduce either dehydroascorbate or ascorbyl radical back to ascorbate by "recycling" vitamin C may contribute to lowering the nutritional requirement of it and to increase tissue antioxidant capacity. The activities of two enzymatic activities, GSH-dehydroascorbate reductase (two-electron reduction pathway) and NADH-semidehydroascorbate reductase (one-electron reduction pathway) in pig tissues, have been investigated. The activity of glutathione-dependent reduction of dehydroascorbate, although measurable, appeared negligible taking into consideration the low physiological substrate concentration. On the other hand, the one-electron reduction of ascorbyl radical resulted fast enough to slow down the consumption of the antioxidant vitamin.
1991
290
458
462
ENZYMATIC RECYCLING OF OXIDIZED ASCORBATE IN PIG-HEART - ONE-ELECTRON VS 2-ELECTRON PATHWAY / Coassin, M; Tomasi, Aldo; Vannini, V; Ursini, F.. - In: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. - ISSN 0003-9861. - STAMPA. - 290:(1991), pp. 458-462.
Coassin, M; Tomasi, Aldo; Vannini, V; Ursini, F.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/11890
Citazioni
  • ???jsp.display-item.citation.pmc??? 9
  • Scopus 70
  • ???jsp.display-item.citation.isi??? 65
social impact