A technology platform to chiral amines: selected examples in asymmetric organocatalysis

Organocatalysis makes use of small organic molecules to activate reaction partners and is nowadays an established catalytic platform; in fact, despite the relatively young age, its potential and powerful impact is widely appreciated. Importantly, organocatalysis, along with metal- and biocatalysis, is routinely screened in industry during the selection process to target compounds of interest. Among these, chiral amines are one of the most important class of target molecules in industry. Herein we present selected approaches in organocatalysis to access chiral amines both from academia and industry.