Historically, melanoma has been typically diagnosed by naked-eye examination and confirmed with invasive biopsy. However, recently the use of reflectance confocal microscopy enables non-invasive bedside diagnosis of clinically equivocal lesions. We present a case in which reflectance confocal microscopy was used to evaluate two skin lesions in the same patient confirming the diagnosis of a melanoma and potentially avoiding invasive biopsy in the second benign melanocytic lesion.  Clinicians should be aware of the availability of new non-invasive technologies that can aid in early diagnosis of malignant skin tumors and potentially reduce the number of benign lesion excisions.

Case Report: Melanoma and melanocytic nevus differentiation with reflectance confocal microscopy / Ludzik, J.; Witkowski, A. M.; Pellacani, G.. - In: F1000RESEARCH. - ISSN 2046-1402. - 4(2015), pp. 257-257. [10.12688/f1000research.6793.1]

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