A Hall device was used for measuring spin polarization on electrons that are either reorganized within the molecules or transmitted through the self-assembled monolayers of DNA adsorbed on the device surface. We were able to observe spin-dependent charge polarization and charge transport through double-stranded DNA of various lengths and through double-stranded DNA containing oxidative damage. We found enhancement in the spin-dependent transport through oxidatively damaged DNA. This phenomenon can be rationalized either by assuming that the damaged DNA is characterized by a higher barrier for conduction or by charge transfer through the DNA being conducted through at least two channels, one involves the bases and is highly conductive but less spin selective, while the other pathway is mainly through the ribophosphate backbone and it is the minor one in terms of charge transmission efficiency, but it is highly spin selective.

Effect of Oxidative Damage on Charge and Spin Transport in DNA / Mishra, S.; Poonia, V. S.; Fontanesi, C.; Naaman, R.; Fleming, A. M.; Burrows, C. J.. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - 141:1(2019), pp. 123-126. [10.1021/jacs.8b12014]

Effect of Oxidative Damage on Charge and Spin Transport in DNA

Fontanesi C.;
2019-01-01

Abstract

A Hall device was used for measuring spin polarization on electrons that are either reorganized within the molecules or transmitted through the self-assembled monolayers of DNA adsorbed on the device surface. We were able to observe spin-dependent charge polarization and charge transport through double-stranded DNA of various lengths and through double-stranded DNA containing oxidative damage. We found enhancement in the spin-dependent transport through oxidatively damaged DNA. This phenomenon can be rationalized either by assuming that the damaged DNA is characterized by a higher barrier for conduction or by charge transfer through the DNA being conducted through at least two channels, one involves the bases and is highly conductive but less spin selective, while the other pathway is mainly through the ribophosphate backbone and it is the minor one in terms of charge transmission efficiency, but it is highly spin selective.
2019
17-dic-2018
141
1
123
126
Effect of Oxidative Damage on Charge and Spin Transport in DNA / Mishra, S.; Poonia, V. S.; Fontanesi, C.; Naaman, R.; Fleming, A. M.; Burrows, C. J.. - In: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. - ISSN 0002-7863. - 141:1(2019), pp. 123-126. [10.1021/jacs.8b12014]
Mishra, S.; Poonia, V. S.; Fontanesi, C.; Naaman, R.; Fleming, A. M.; Burrows, C. J.
File in questo prodotto:
File Dimensione Formato  
JACS_DNA_2019.8b12014.pdf

Accesso riservato

Tipologia: Versione pubblicata dall'editore
Dimensione 1.24 MB
Formato Adobe PDF
1.24 MB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1181719
Citazioni
  • ???jsp.display-item.citation.pmc??? 5
  • Scopus 31
  • ???jsp.display-item.citation.isi??? 28
social impact