Water-soluble MBHA derivatives were found to self-assemble in a water environment to generate aggregates showing core-shell architectures. The aggregates appeared to be capable of working as nanoreactors performing a multi-functionalization of poly-histidine fragments, which after an initial interaction with the solvated oligo(ethylene glycol) shell reach the reactive core.
Nanoreactors for the multi-functionalization of poly-histidine fragments / Paolino, M.; Reale, A.; Razzano, V.; Giuliani, G.; Donati, A.; Bonechi, C.; Caselli, G.; Visintin, M.; Makovec, F.; Scialabba, C.; Licciardi, M.; Paccagnini, E.; Gentile, M.; Salvini, L.; Tavanti, F.; Menziani, M. C.; Cappelli, A.. - In: NEW JOURNAL OF CHEMISTRY. - ISSN 1144-0546. - 43:18(2019), pp. 6834-6837. [10.1039/c9nj00279k]
Nanoreactors for the multi-functionalization of poly-histidine fragments
Tavanti F.Investigation
;Menziani M. C.Conceptualization
;
2019
Abstract
Water-soluble MBHA derivatives were found to self-assemble in a water environment to generate aggregates showing core-shell architectures. The aggregates appeared to be capable of working as nanoreactors performing a multi-functionalization of poly-histidine fragments, which after an initial interaction with the solvated oligo(ethylene glycol) shell reach the reactive core.
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