The incidence of squamous cell carcinoma of the anal canal (SCAC) is increasing in both sexes but the standard treatment remains that of 20 years ago. However, interesting data have recently emerged on the use of anti-epidermal growth factor receptor (EGFR) agents and immunotherapy in advanced disease. Thus, new avenues of research are opening up that will hopefully lead to more effective therapeutic strategies. We provide an overview of the latest studies published on this tumor and discuss the possible future therapeutic options for combination therapy, anti-EGFR treatment and radiotherapy.

Treatment of squamous cell carcinoma of the anal canal: A new strategies with anti-EGFR therapy and immunotherapy / Casadei Gardini, A.; Passardi, A.; Fornaro, L.; Rosetti, P.; Valgiusti, M.; Ruscelli, S.; Monti, M.; Casadei, C.; Pagan, F.; Frassineti, G. L.. - In: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. - ISSN 1040-8428. - 123:(2018), pp. 52-56. [10.1016/j.critrevonc.2018.01.007]

Treatment of squamous cell carcinoma of the anal canal: A new strategies with anti-EGFR therapy and immunotherapy

Casadei Gardini, A.
;
Fornaro, L.;Ruscelli, S.;Casadei, C.;
2018

Abstract

The incidence of squamous cell carcinoma of the anal canal (SCAC) is increasing in both sexes but the standard treatment remains that of 20 years ago. However, interesting data have recently emerged on the use of anti-epidermal growth factor receptor (EGFR) agents and immunotherapy in advanced disease. Thus, new avenues of research are opening up that will hopefully lead to more effective therapeutic strategies. We provide an overview of the latest studies published on this tumor and discuss the possible future therapeutic options for combination therapy, anti-EGFR treatment and radiotherapy.
2-feb-2018
123
52
56
Treatment of squamous cell carcinoma of the anal canal: A new strategies with anti-EGFR therapy and immunotherapy / Casadei Gardini, A.; Passardi, A.; Fornaro, L.; Rosetti, P.; Valgiusti, M.; Ruscelli, S.; Monti, M.; Casadei, C.; Pagan, F.; Frassineti, G. L.. - In: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. - ISSN 1040-8428. - 123:(2018), pp. 52-56. [10.1016/j.critrevonc.2018.01.007]
Casadei Gardini, A.; Passardi, A.; Fornaro, L.; Rosetti, P.; Valgiusti, M.; Ruscelli, S.; Monti, M.; Casadei, C.; Pagan, F.; Frassineti, G. L.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1177412
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